Fatemeh Pakniyat

Development of a Radiomics-Based Machine Learning Model Utilizing CT-Guided Biopsy Images: Virtual Biopsy of Thoracic Cancers

Maryam Cheraghi, Mehran Malekshoar, Fatemeh Pakniyat, Seyed Mahmoud Reza Aghamiri et autres

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Plasma-activated medium as a radiosensitizer in bladder cancer: an in vitro study

Hanieh Nazem Zomorodi, Masoumeh Zangeneh, Aziz Mahmoudzadeh, Fatemeh Pakniyat et autres

Abstract Plasma-activated medium (PAM), generated through exposure to cold atmospheric plasma (CAP), has emerged as a novel anticancer approach with promising radiosensitizing properties, offering potential to enhance the therapeutic efficacy of radiotherapy by increasing tumor cell susceptibility to ionizing radiation. This study …

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Cytogenetic and cytotoxic effects of melatonin and saffron on lymphocytes of luminal A and luminal B breast cancer patients irradiated in vitro

Hossein Mozdarani, S. Mozdarani, Fatemeh Pakniyat, Hassan Nosrati

Background: Due to high radiation-sensitivity of breast cancer (BC) patients, use of radioprotectors to ameliorate the deleterious effects of radiation could be a priority.This study aimed to evaluate the reducing effects of saffron and melatonin on ionizing radiation-induced damages in lymphocytes of …

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Bystander Response Following High-Dose X-irradiation; Time-dependent Nature of GammaH2AX Foci and Cell Death Consequences

Fatemeh Pakniyat, Hossein Mozdarani, Hassan Ali Nedaei, Aziz Mahmoudzadeh et autres

Background: The paradigm shifts in target theory could be defined as the radiation-triggered bystander response in which the radiation deleterious effects occurred in the adjacent cells. Objective: This study aims to assess bystander response in terms of DNA damage and their possible …

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Evaluation of Capability and Relationship of Different Radiobiological Endpoints for Radiosensitivity Prediction in Human Tumor Cell Lines Compared with Clonogenic Survival

Fatemeh Pakniyat

Background: Establishing a predictive assay of radiosensitivity (as an appropriate, practical and cost-effective method) has been challenging. Objective: The purpose of this study is to evaluate the capability and relationship of various endpoints, including GammaH2AX, micronuclei; and apoptosis in determining the human …

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Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury

Guillaume Favre, Sara Mazzetti, Carole Gengler, Claire Bertelli et autres

Neonatal COVID-19 is rare and mainly results from postnatal transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), however, can infect the placenta and compromise its function. We present two cases of decreased fetal movements and abnormal fetal heart rhythm 5 days after …

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Effects of saffron extract on the frequency of radiation induced chromosomal aberration in G-2-lymphocytes of normal individuals and breast cancer patients

Hossein Mozdarani, Fatemeh Pakniyat, Sahar Mozdarani, Hassan Nosrati

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Effects of saffron extract on the frequency of radiation induced chromosomal aberration in G-2-lymphocytes of normal individuals and breast cancer patients

Hossein Mozdarani, Fatemeh Pakniyat, S. Mozdarani, Hassan Nosrati

Effects of saffron extract on the frequency of radiation induced chromosomal aberration in G 2 -lymphocytes of normal individuals and breast cancer patientsfactors, such as age, life style, oxidative stress, genetic predisposition and various genes involved in the response to radiation induced …

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Management of bulky high-grade pleomorphic sarcoma using grid therapy technique

Sanaz Tajiki, Somayeh Gholami, Ali Kazemian, Peyman Haddad et autres

In the present study, a case was reported concerning a patient with a bulky extremity soft tissue sarcoma treated with spatially fractionated Grid therapy and then followed by standard external beam radiotherapy. Treatment was performed using a Grid block to deliver 15 …

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Enhanced response of radioresistant carcinoma cell line to heterogeneous dose distribution of grid; the role of high-dose bystander effect

Fatemeh Pakniyat, Hassan Ali Nedaie, Hossein Mozdarani, Aziz Mahmoudzadeh et autres

Purpose The classical dogma that restricted the radiation effect to the directly irradiated cells has been challenged by the bystander effect. This off-target phenomenon which was manifested in adjacent cells via signaling of fully exposed cells might be involved in high-dose Grid …

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Demonstration of bystander response in high dose technique of grid using theoretical calculation by linear quadratic model along with experimental investigations

Fatemeh Pakniyat, Somayeh Gholami, Hassan Ali Nedaie, Hossein Mozdarani et autres

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Radiation-induced bystander effect following hypo- fraction technique of grid therapy by use of sensitive molecular markers

Fatemeh Pakniyat, Hassan Ali Nedaie, Hossein Mozdarani, Amir Mahmoodzadeh et autres

Introduction: Radiation-induced bystander effect (RIBE) is a well-known response associated with the induction of radiation effects in non-irradiated cells via signaling of hit ones. As this so-called phenomenon has been largely investigated in low dose levels, few studies focused on higher dose …

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