Mohammad Sadraeian

Quantum spectroscopy with undetected photons for biomolecular sensing in the mid-infrared

Mahya Mohammadi, Meryem-Nur Duman, Isa Ahmadalidokht, Mohammad Sadraeian et autres

We investigate numerical modelling of quantum spectroscopy with undetected photons for protein detection in the mid-infrared spectral region. Classical Fourier-transform infrared spectroscopy of protein samples (bovine serum albumin and N-terminal pro-brain natriuretic peptide) is used as reference to define the sample’s mid-infrared …

au (code pays fourni par la source)

Quantum Spectroscopy with Undetected Photons for Biomolecular Sensing in the Mid-Infrared

Mahya Mohammadi, Meryem-Nur Duman, Isa Ahmadalidokht, Mohammad Sadraeian et autres

au (code pays fourni par la source)

Quantum Spectroscopy with Undetected Photons for Biomolecular Sensing in the Mid-Infrared

Mahya Mohammadi, Meryem-Nur Duman, Isa Ahmadalidokht, Mohammad Sadraeian et autres

We investigate quantum spectroscopy with undetected photons for protein detection in the mid-infrared spectral region. Classical Fourier-transform infrared spectroscopy of protein samples (bovine serum albumin and N-terminal pro-brain natriuretic peptide) is used as reference to define the sample's mid-infrared absorption, which is …

Quantum Spectroscopy with Undetected Photons for Biomolecular Sensing in the Mid-Infrared

Mahya Mohammadi, Meryem-Nur Duman, Isa Ahmadalidokht, Mohammad Sadraeian et autres

We investigate quantum spectroscopy with undetected photons for protein detection in the mid-infrared spectral region. Classical Fourier-transform infrared spectroscopy of protein samples (bovine serum albumin and N-terminal pro-brain natriuretic peptide) is used as reference to define the sample's mid-infrared absorption, which is …

au (code pays fourni par la source)

Beads‐on‐a‐Tip testing for ultrasensitive antigen detection across a large dynamic range

Ziwei Wu, Yangjian Cai, Yitong Zhao, Mahnaz Maddahfar et autres

Lateral flow immunoassays (LFIAs) are low-cost, rapid, and easy to use for point-of-care testing (POCT), but the majority of the available LFIA tests are indicative, rather than quantitative, and their sensitivity in antigen tests are usually limited at the nanogram range, which …

au, cn (code pays fourni par la source)

Heterogeneity of Upconversion Bioconjugates Revealed by Single Nanoparticle Spectroscopy

Farrel Rafaelino Separgo, Yangjian Cai, Yitong Zhao, Mahnaz Maddahfar et autres

Lanthanide-doped upconverting nanoparticles (UCNPs) are promising for bioimaging and biosensing, with functionality often relying on conjugation to biomolecules, such as antibodies, for specific recognition. However, the factors governing the consistency and repeatability of nanoconjugate performance are often overlooked due to difficulties in …

au, us (code pays fourni par la source)

A Pipette-Tip-Based Point-of-Care Test Platform for Detection of MicroRNA at Subfemtomolar Concentrations Using Upconverting Nanoparticles on Microbeads

Mohammad Sadraeian, Jiajia Zhou, Jiayan Liao, Jawairia Umar Khan et autres

MicroRNAs are potent early disease biomarkers, yet ultrasensitive assays suitable for point-of-care testing (POCT) remain scarce. We present a pipet-tip platform for quantitative detection of oncogenic miR-27a. This method employs a sandwich hybridization strategy utilizing biotinylated capture oligos on microbeads and upconversion …

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mRNA Fate in Human Cells; Degradation and Subcellular Localisation

Kamalpreet Kaur, Jawairia Umar Khan, Farah Al Hlow, Mohammad Sadraeian et autres

The fate of mRNA in human cells is a critical aspect of gene regulation, encompassing both post-translation degradation and subcellular localization. This review explores the critical role of mRNA fate in human cells, focusing on post-translation degradation and subcellular localization. mRNA degradation, …

au, ir (code pays fourni par la source)

Harnessing thiophilic cadmium to enhance 8–17 DNAzyme activity in cascade oligo biosensors

Mohammad Sadraeian, Reza Maleki, Libing Fu, Gungun Lin et autres

au (code pays fourni par la source)

Electrokinetically Driven On-Fiber Active Lateral Flow Assay for MicroRNA Detection

Jawairia Umar Khan, Gungun Lin, Mohammad Sadraeian, Yuen Yee Cheng et autres

MicroRNAs are promising for early disease detection, particularly in oncology. Their small size ensures stability in biospecimens, but low concentrations require either molecular amplification or large sample volumes, posing challenges toward point-of-care testing (POCT). Here, we present a rapid approach for detecting …

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Spectroscopy with Undetected Photons for Biomedical Diagnostics in Mid-Infrared

Mahdad Mohammadi, Isa Ahmadalidokht, Mohammad Sadraeian, Lana McClements et autres

This study introduces quantum spectroscopy using entangled photon pairs as a practical technique for detecting critical biomarkers in fluid samples. By employing visible (VIS) light sources and detectors, this method offers a reduction in cost and complexity compared to traditional methods such …

au (code pays fourni par la source)

Bacterial nanotechnology as a paradigm in targeted cancer therapeutic delivery and immunotherapy

Ahmad Gholami, Milad Mohkam, Saeede Soleimanian, Mohammad Sadraeian et autres

Cancer, a multifaceted and diverse ailment, presents formidable obstacles to traditional treatment modalities. Nanotechnology presents novel prospects for surmounting these challenges through its capacity to facilitate meticulous and regulated administration of therapeutic agents to malignant cells while concurrently modulating the immune system …

ir, au (code pays fourni par la source)