Dirk Gerdes

Poster session 1Cell growth, differentiation and stem cells - Heart72Understanding the metabolism of cardiac progenitor cells: a first step towards controlling their proliferation and differentiation?73Expression of pw1/peg3 identifies a new cardiac adult stem cell population involved in post-myocardial infarction remodeling74Long-term stimulation of iPS-derived cardiomyocytes using optogenetic techniques to promote phenotypic changes in E-C coupling75Benefits of electrical stimulation on differentiation and maturation of cardiomyocytes from human induced pluripotent stem cells76Constitutive beta-adrenoceptor-mediated cAMP production controls spontaneous automaticity of human induced pluripotent stem cell-derived cardiomyocytes77Formation and stability of T-tubules in cardiomyocytes78Identification of miRNAs promoting human cardiomyocyte proliferation by regulating Hippo pathway79A direct comparison of foetal to adult epicardial cell activation reveals distinct differences relevant for

E. André, Elisa Yaniz‐Galende, Charles Hamilton, Gregory J. Dusting et autres

Emerging evidence supports a mandatory metabolic shift from glycolysis to oxidative phosphorylation during stem cells differentiation. In this study, we investigate cardiac progenitor cells (CPC) metabolic adaptations to a hypoxic environment and the bioenergetic transition underlying cardiomyocyte differentiation process. We intend to …

Association of testosterone and dihydrotestosterone with externalizing behavior in adolescent boys and girls

Athanasios Maras, Manfred Laucht, Dirk Gerdes, Cindy Wilhelm et autres

de (code pays fourni par la source)

CD1d structure and regulation on human thymocytes, peripheral blood T cells,B cells and monocytes

Mark A. Exley, Joe G. N. Garcia, S. Brian Wilson, Fabio Spada et autres

Human T cells expressing CD161 and an invariant T-cell receptor (TCR) alpha-chain (Valpha24invt T cells) specifically recognize CD1d and appear to have immunoregulatory functions. However, the physiological target cells for this T-cell population, and whether alterations in CD1d expression contribute to the …

us, at (code pays fourni par la source)

Rapid, Nongenomic Steroid Actions: A New Age?

Bernhard M. W. Schmidt, Dirk Gerdes, Martin Feuring, Elisabeth Falkenstein et autres

de (code pays fourni par la source)

Nongenomic Actions of Steroids - From the Laboratory to Clinical Implications

Dirk Gerdes, Michael Christ, K Haseroth, A Notzon et autres

In the classical concept of steroid action, steroids bind to cytoplasmic receptors and modulate nuclear transcription after translocation of steroid-receptor complexes into the nucleus. Due to similarities of molecular structure, receptors for steroids, retinoids, vitamin D3 and thyroid hormone are considered to …

de (code pays fourni par la source)

Specific Progesterone Binding to a Membrane Protein and Related Nongenomic Effects on Ca2+-Fluxes in Sperm

Elisabeth Falkenstein, Marina Heck, Dirk Gerdes, D. Forssmann Grube et autres

Rapid, nongenomic effects of steroids are supposed to be transmitted by membrane receptors unrelated to the classic intracellular steroid receptors. In this context, a putative progesterone membrane binding protein (mPR) has been identified, recently. Here we show that expression of mPR-cDNA in …

de, us (code pays fourni par la source)

Rapid Nongenomic Effects of Aldosterone in Mineralocorticoid-Receptor-Knockout Mice

K Haseroth, Dirk Gerdes, Stefan Berger, Martin Feuring et autres

de (code pays fourni par la source)

Functional expression and characterisation of a progesterone membrane receptor

Elisabeth Falkenstein, Dirk Gerdes, Martin Wehling

Regionalismus in Europa

Dirk Gerdes

Am 18.11.1988 verabschiedete das Europäische Parlament eine Entschließung zur Regionalpolitik sowie ein Grundsatzpapier, das als ‚Regionalisierungscharta ‘(Hrbek/Weyand 1994: 177–181) bekannt wurde. Während die Regionalisierungscharta mit ihrer vergleichsweise präzisen Regionsdefinition den seinerzeit erreichbaren Konsens auf europäisch-parlamentarischer Ebene spiegelte, werden die ‚Regionsabgrenzungen ‘der Kommission …

Localization of a putative progesterone membrane binding protein in porcine hepatocytes.

Elisabeth Falkenstein, Kerstin Schmieding, Aksel Lange, Carmen Meyer et autres

A putative membrane bound steroid receptor was localized using a peptide specific antibody. Surprisingly, the distribution of immunocytochemical staining in porcine hepatocytes cells provides evidence for the localization to endomembranes (endoplasmic reticulum, Golgi apparatus). Immunofluorescence experiments with HEK cells, which were transfected …

de (code pays fourni par la source)

Short Communication

Dirk Gerdes, Martin Wehling, Barbara Leube, Elisabeth Falkenstein

We have cloned two human putative steroid binding membrane proteins, termed Hpr6.6 and Dg6. Hpr6.6 is the human homolog of a previously cloned porcine progesterone binding protein. Both proteins contain a putative transmembrane domain and a highly conserved stretch of 58 amino …

de (code pays fourni par la source)

Intraepithelial lymphocytes in normal human intestine do not express proteins associated with cytolytic function.

Andreas Chott, Dirk Gerdes, Alexandra Spooner, Isabella Mosberger et autres

Human small intestine contains a very large population of intraepithelial T lymphocytes (IELs) that are oligoclonal, appear functionally to be cytolytic T cells, and may contribute to the normal and pathological turnover of intestinal epithelial cells. This report addresses the cytolytic function …

us (code pays fourni par la source)