Marta Murillo

Recomendaciones clínicas para el manejo de pacientes con diabetes tipo 1 en situaciones especiales

Estela Gil Poch, Marta Ferrer Lozano, Marta Murillo, Roque Cardona‐Hernandez et autres

Exercise-Induced Immune Modulation in Type 1 Diabetes: From Mechanisms to Clinical Perspectives

Daniel A Cook, David Perna‐Barrull, Marta Murillo, Marta Vives‐Pi

Type 1 diabetes is a chronic autoimmune disease driven by immune-mediated destruction of pancreatic β-cells. While technological advances in insulin delivery and glucose monitoring have improved glycemic management, they do not address the underlying autoimmune process. Identifying low-risk adjunct strategies that can …

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Early metabolic alterations in pediatric obesity: Depot-specific insights from untargeted adipose tissue metabolomics

Ángeles López‐Gonzálvez, Cristina Muñoz-San Martín, Andrea Soria-Gondek, Belén Fernández Requena et autres

BACKGROUND: Childhood obesity is associated with lifelong metabolic risk, yet depot-specific alterations in adipose tissue metabolism during early life remain poorly understood. OBJECTIVE: This study aimed to characterize the metabolic differences between subcutaneous (sWAT) and visceral white adipose tissue (vWAT) in pediatric …

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Subcutaneous and visceral adipose tissue lipidome in children reveals novel lipid species involved in obesity

Andrea Soria-Gondek, Carolina Gonzalez-Riano, Pablo Fernandez-Garcia, Belén Fernández Requena et autres

Overweight impacts over 390 million children and adolescents worldwide, of whom around 160 million are living with obesity. Adipose tissue biology in pediatric obesity is still relatively unknown. Adaptations to obesity including fat mobilization and remodeling are being investigated. The objective was …

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Obesidad en adolescentes: la clave del diagnóstico diferencial desde atención primaria

Daniela Ardila, Judit Alós, Marta Murillo, María Mendez

Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study

Lorena González, Carolina González-Riaño, Pablo Fernández‐García, Rubén Cereijo et autres

Abstract Recombinant human growth hormone (rhGH) therapy is the primary treatment for children born small for gestational age (SGA) who fail to show spontaneous catch-up growth by two or four years. While its effects on white adipose tissue are well-documented, this pilot …

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Identification of Peripheral Blood Endotypes Associated With Age in Pediatric Type 1 Diabetes

Laia Gómez-Muñoz, David Perna‐Barrull, Paula Sol Ventura, Aina Valls et autres

Aims: This study aimed to identify age‐related peripheral immune endotypes in pediatric patients with type 1 diabetes (T1D) at disease onset and assess their metabolic control 1 year post‐diagnosis. Methods: Immune cell subpopulations (T and B lymphocytes, myeloid cells, and natural killer …

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Corrigendum: Candidate biomarkers for the prediction and monitoring of partial remission in pediatric type 1 diabetes

Laia Gómez-Muñoz, David Perna‐Barrull, Josep M. Caroz-Armayones, Marta Murillo et autres

[This corrects the article DOI: 10.3389/fimmu.2022.825426.].

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Corrigendum: NK cell subsets changes in partial remission and early stages of pediatric type 1 diabetes

Laia Gómez-Muñoz, David Perna‐Barrull, Adrian Villalba, Silvia Rodríguez-Fernández et autres

[This corrects the article DOI: 10.3389/fimmu.2020.611522.].

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Lipidome Profiling in Childhood Obesity Compared to Adults: A Pilot Study

Andrea Soria‐Gondek, Pablo Fernández‐García, Lorena González, Marjorie Villalobos Reyes et autres

The objective is to assess the circulating lipidome of children with obesity before and after lifestyle intervention and to compare the data to the circulating lipidome of adults with obesity before and after bariatric surgery. Ten pediatric (PE) and thirty adult (AD) …

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Impact of COVID19 pandemic on patients with rare diseases in Spain, with a special focus on inherited metabolic diseases

M. Mar Rovira‐Remisa, Mónica Moreira, Paula Sol Ventura, Pablo González-Álvarez et autres

Introduction: The Covid-19 pandemic soon became an international health emergency raising concern about its impact not only on physical health but also on quality of life and mental health. Rare diseases are chronically debilitating conditions with challenging patient care needs. We aimed …

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Immunoregulatory Biomarkers of the Remission Phase in Type 1 Diabetes: miR-30d-5p Modulates PD-1 Expression and Regulatory T Cell Expansion

Laia Gómez-Muñoz, David Perna‐Barrull, Marta Murillo, María Pilar Armengol et autres

The partial remission (PR) phase of type 1 diabetes (T1D) is an underexplored period characterized by endogenous insulin production and downmodulated autoimmunity. To comprehend the mechanisms behind this transitory phase and develop precision medicine strategies, biomarker discovery and patient stratification are unmet …

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