Profil bibliographique

Marc Cabry

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

2Publications signalées
8Citations signalées
1Affiliations récentes

Les institutions déclarées

Institute of Cancer Research

Les domaines associés

Protein Structure and DynamicsCancer-related Molecular PathwaysHeat shock proteins researchUbiquitin and proteasome pathwaysEnzyme Structure and Function

Les publications récentes

Accès ouvert 2024 article OpenAlex

Specific radiation damage to halogenated inhibitors and ligands in protein–ligand crystal structures

Matthew J. Rodrigues, Marc Cabry, Gavin W. Collie, Michael W. Carter et autres

Protein–inhibitor crystal structures aid medicinal chemists in efficiently improving the potency and selectivity of small-molecule inhibitors. It is estimated that a quarter of lead molecules in drug discovery projects are halogenated. Protein–inhibitor crystal structures have shed light on the role of halogen …

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3 citations Journal of Applied Crystallography
2021 conference-abstract OpenAlex

Abstract LBA004: Identification of GSPT1-directed molecular glue degrader (MGD) for the treatment of Myc-driven breast cancer

Gérald Gavory, Bernhard Fasching, Débora Bonenfant, Amine Sadok et autres

Abstract The Myc family of transcription factors is a well-established driver of human cancers. However, despite being amongst the most frequently mutated, translocated and overexpressed oncogenes, no therapy directly targeting the Myc family members has been developed to date. Abnormal activation of …

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5 citations Molecular Cancer Therapeutics
Profil ORCIDNotice OpenAlex

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