María José Ramírez‐Lázaro

Update on the Prevalence, Incidence, Mortality, and Trends in Treatment of Inflammatory Bowel Disease in a Population-Based Registry in Catalonia Between 2017 and 2023

Eduard Brunet, Belén García-Sagué, Emili Vela, Caridad Pontes et autres

Background: The prevalence of inflammatory bowel disease (IBD) is increasing worldwide, while the incidence is tending to stabilize. Moreover, the use of biological treatments is increasing; some studies suggest that surgeries and hospitalizations are decreasing instead. Methods: A population-based, retrospective cohort study …

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Prevalence, Incidence, Mortality and Trends in Treatment of Inflammatory Bowel Disease in Catalonia Between 2017 and 2023. An Epidemiological Update

Belén García-Sagué, Emili Vela, Caridad Pontes, Luigi Melcarne et autres

Background: Prevalence of inflammatory bowel disease (IBD) is increasing worldwide, while incidence is tending to stabilize. Moreover, the use of biological treatments is increasing, some studies suggest that surgeries and hospitalizations are decreasing instead. Methods: A population-based, retrospective cohort study was conducted …

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Monthly intravenous maintenance treatment with ustekinumab regains clinical response in patients with Crohn’s disease who no longer respond to the drug when administered subcutaneously

Berta López‐Sáez, Ariadna Altadill, Eduard Brunet, Belén García-Sagué et autres

Background: Several studies have assessed the efficacy of re-induction and subcutaneous intensification of ustekinumab (UST) to regain clinical remission of inflammatory bowel disease (IBD). However, very few have evaluated the effectiveness of intravenous UST for this purpose. Objectives: The aims of the …

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Sa1861: TREATMENT AND OUTCOMES TIME TRENDS OF PEDIATRIC CROHN’S DISEASE IN CATALONIA FROM 2011 TO 2023.

Eduard Brunet, Inés Loverdos, Emili Vela, Clara Comalrena de Sobregrau et autres

Sa1870: PREVALENCE, INCIDENCE AND MORTALITY OF PEDIATRIC INFLAMMATORY BOWEL DISEASE IN CATALONIA

Eduard Brunet, Inés Loverdos, Emili Vela, Clara Comalrena de Sobregrau et autres

Identification and ultrasensitive quantification of H. pylori infections on gastric and stool human samples with a photonic label-free nanobiosensor

Alejandro Astúa, M.‐Carmen Estévez, María José Ramírez‐Lázaro, Xavier Calvet et autres

Helicobacter pylori is a widespread bacterium that infects the stomach, causing gastric disorders associated with high morbidity and mortality worldwide. Current methods for identifying and quantifying this pathogen rely on invasive and non-invasive tests. Although combining these methods allows accurate diagnosis, they …

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P-62 - PREVALENCIA, INCIDENCIA Y MORTALIDAD DE LA ENFERMEDAD INFLAMATORIA INTESTINAL PEDIÁTRICA EN CATALUÑA

Mar Salas Llopart, Inés Loverdos, Emili Vela, Clara Comalrena de Sobregrau et autres

P-63 - TENDENCIAS TEMPORALES EN EL TRATAMIENTO Y LOS RESULTADOS DE LA ENFERMEDAD DE CROHN PEDIÁTRICA EN CATALUÑA DESDE 2021 HASTA 2023

Judith Cortada, Inés Loverdos, Emili Vera, Clara Comalrena de Sobregrau et autres

Economic impact of inflammatory bowel disease in Catalonia: a population-based analysis

Eduard Brunet, Belén García-Sagué, Emili Vela, Luigi Melcarne et autres

Background: Inflammatory bowel disease (IBD) has a major economic impact on healthcare costs. Objectives: The aim of this study was to evaluate the current healthcare expenditure associated with IBD in a population-wide study in Catalonia. Design: Retrospective observational study. Methods: All patients …

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Incidence of Myelotoxicity and Other Adverse Effects Related to Thiopurine Starting in Patients with Inflammatory Bowel Disease: Retrospective Observational Study in a Third-Level Hospital

Gerard Grau, Eduard Brunet, Laura Patricia Llovet, Patricia Pedregal-Pascual et autres

Background and objectives: Thiopurines are an effective treatment for the maintenance of remission in inflammatory bowel disease (IBD). They can present adverse effects (AEs), with myelotoxicity being the most relevant. This study aims to determine the incidence of AEs related to the …

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Coding and non-coding co-expression network analysis identifies key modules and driver genes associated with precursor lesions of gastric cancer

Sergio Lario, María José Ramírez‐Lázaro, Anna Brunet‐Vega, María Vila-Casadesús et autres

BACKGROUND: Helicobacter pylori infection is the most important risk factor for gastric cancer (GC). Human gastric adenocarcinoma develops after long-term H. pylori infection via the Correa cascade. This carcinogenic pathway describes the progression from gastritis to atrophy, intestinal metaplasia (IM), dysplasia and …

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Follow-Up Study Confirms the Presence of Gastric Cancer DNA Methylation Hallmarks in High-Risk Precursor Lesions

Antonio Gómez, Miguel L. Pato, Luís Bujanda, Núria Sala et autres

To adopt prevention strategies in gastric cancer, it is imperative to develop robust biomarkers with acceptable costs and feasibility in clinical practice to stratified populations according to risk scores. With this aim, we applied an unbiased genome-wide CpG methylation approach to a …

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