Beatriz Palacios

Non–technique-related healthcare utilization and costs among dialysis and kidney transplant recipients in Spain: a real-world analysis

Rafael Santamaria, Carlos Escobar, Unai Aranda, Beatriz Palacios et autres

Kidney failure requiring kidney replacement therapy (KRT) is associated with a substantial and growing economic burden. While the costs directly attributable to KRT modalities are well documented, the resource use and costs unrelated to KRT modalities remain unclear. To quantify healthcare resource …

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Sex Differences in Heart Failure Epidemiology and Clinical Characteristics in Spain: A Nationwide Population-Based Study

Andrea Severo Sánchez, Diego Alvaredo Rodrigo, Javier González Martín, Sonia Rivas García et autres

Background: Heart failure (HF) is a major public health problem and a paradigmatic condition for sex differences in cardiovascular disease. However, national population-based evidence describing these differences remains limited. We aimed to provide the first nationwide sex-stratified epidemiologic characterization of HF in …

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Trends in the management and coding of chronic kidney disease in Spain: cross-sectional analyses of real-life data with a 5-year interval

Rafael Santamaría, Belén Pimentel, Beatriz Palacios, Ignacio Hernández et autres

Rafael Santamaría, Belén Pimentel, Beatriz Palacios, Ignacio Hernández, Carlos Escobar, Manuel Gorostidi, Ana Cebrian, Roberto Alcázar; Trends in the manag

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CKD as an independent driver of polypharmacy

Rafael Santamaria, Carlos Escobar, Ignacio Hernández, Beatriz Palacios et autres

Rafael Santamaria, Carlos Escobar, Ignacio Hernández, Beatriz Palacios, Unai Aranda, Roberto Alcázar; CKD as an independent driver of polypharmacy, Clinica

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Incidence and outcomes of major bleeding among first-time oral factor Xa inhibitor users: multinational observational cohort studies

Alexander T. Cohen, Robert C. Welsh, Jenneke Leentjens, Ali Canbay et autres

Background: Despite the favorable risk-benefit profile of factor (F)Xa inhibitors (FXai) vs vitamin K antagonists, major bleeding remains a concern. Objectives: This study sought to describe the incidence and mortality rates of major bleeding in FXai-treated patients using large national registries. Methods: …

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Healthcare resource utilization and costs of chronic kidney disease in Spain across KDIGO categories: Insights from real-world evidence

Rafael Santamaria, Carlos Escobar, Unai Aranda, Beatriz Palacios et autres

To determine the healthcare resource utilization and costs in patients with chronic kidney disease (CKD) across the KDIGO stages in real-world clinical practice in Spain. Observational, retrospective study using the BIG-PAC database. Adults with ≥1 measurement of estimated glomerular filtration rate (eGFR) …

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A value-based analysis of the systematic use of dapagliflozin in patients with heart failure

H Bueno, Jorge Íván Bonilla Vélez, Miguel Hernández, Beatriz Palacios et autres

Abstract Background and Purpose Sodium-glucose cotransporter-2 (SGLT2) inhibitors are a cornerstone in the treatment of heart failure (HF) as these are effective and cost-effective. However, their impact on the balance between relevant patient outcomes and healthcare costs are not well known. This …

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Resultados clínicos, uso de recursos sanitarios y costes según la función renal en pacientes con insuficiencia cardiaca

Martín Romo, Claudia Yuste, Jorge Íván Bonilla Vélez, Miguel Hernández et autres

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Cardiovascular and renal outcomes according to KDIGO stages of chronic kidney disease in the Spanish population: Insights from real-world evidence

Rafael Santamaría, Carlos Escobar, Unai Aranda, Beatriz Palacios et autres

OBJECTIVE: Real-world analysis of the clinical profile, treatments, major adverse cardiovascular and renal events (MACE and MARE) in patients with different stages of chronic kidney disease (CKD) as defined by KDIGO guidelines. METHODS: This was an observational, retrospective study using the BIG-PAC …

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Clinical outcomes, health care resource utilization and costs by renal function in patients with heart failure

Martín Romo, Claudia Yuste, Jorge Íván Bonilla Vélez, Miguel Hernández et autres

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Utilization of Evidence Blueprint Initiative to Transform Capability Development in AstraZeneca Spain

Jesús Medina, Joaquín Sánchez-Covisa, Javier Nuevo, Beatriz Palacios et autres

The role of Medical Affairs (MA) has shifted from traditional evidence dissemination to an integrated process leveraging real-world data (RWD) and diverse data sources. To adapt and lead this shift, AstraZeneca (AZ) Spain recognized the essential need to identify gaps in evidence-generation …

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Quality of Life and Experience of Patients with Heart Failure with Preserved Ejection Fraction and Their Caregivers

Raül Rubio Renau, Beatriz Palacios, Luis Varela, Martín Gutiérrez et autres

Background/Objectives: Evidence of patient experiences with heart failure with preserved ejection fraction (HFpEF) and disease impact on quality of life (QoL) is scarce. This study explored perceived impacts on QoL and healthcare experiences of HFpEF patients and their caregivers. Methods: This was …

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