Lini Liu

The Role of Mirtazapine in the Pathogenesis and Therapy of Chronic Liver Disease

Yuqing Yang, Jing Wu, Xiaojun Li, Dong Hun Yang et autres

Depression is a common comorbidity in patients with chronic liver disease (CLD) and is associated with poorer clinical outcomes. Due to concerns about hepatic metabolism and limited tolerability, the use of traditional antidepressants is often restricted. Mirtazapine is a noradrenergic and specific …

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Significance of left ventricular strain in cardiac magnetic resonance for short-term prognosis in pediatric patients with acute lymphoblastic leukemia

Wenfeng Jin, Jia Ying Yang, Yi Liao, Linjun Xie et autres

BACKGROUND: The survival rate of pediatric leukemia patients has remarkably increased. Early identification of cardiotoxicity associated with chemotherapy and the detection of prognostic factors are essential for effective patient management. OBJECTIVE: To evaluate the prognostic value of parameters assessed by cardiac magnetic …

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Cardiac magnetic resonance T2 mapping and T2* mapping for myocardial iron detection in iron-water phantom models and pediatric patients with transfusion-dependent thalassemia: a comparison study

Hang Fu, Mei Yan, Xue Yang, Ke Xu et autres

Background: The cardiac magnetic resonance (CMR) T2* mapping technique is widely used to quantify myocardial iron and assess iron overload in patients with transfusion-dependent thalassemia (TDT). However, the value of T2 mapping in detecting iron overload and its consistency with T2* mapping …

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Effect of Antidepressants on Non-alcoholic Fatty Liver Disease and their Underlying Mechanism

Hailing Peng, Yumin Qing, Liu Han, Shifeng Fu et autres

INTRODUCTION: The high prevalence of non-alcoholic Fatty Liver Disease (NAFLD), a chronic progressive disease characterized by hepatic steatosis, poses a serious burden to human health. Depression and NAFLD share some common pathogenic mechanisms, and patients with depression are at an increased risk …

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Prognostic value of myocardial strain after chemotherapy in children with leukemia: a cardiac magnetic resonance study

Rong Hua Xu, Wei Huang, Lini Liu, Xiaoyong zhang et autres

The stage of chemotherapy in children with ALL is a long process, and the myocardial damage caused by chemotherapy is still unknown. The different chemotherapy stages may have different degrees of myocardial damage. In this study, cardiac magnetic resonance was used to …

Genetic Causal Associations between Various Serum Minerals and Risk of Depression: A Mendelian Randomization Study

Yuan Wang, Lini Liu, Dong Yang

BACKGROUND: Previous observational studies have discovered a connection between depression and mineral status. Confirming this potential connection is challenging due to confounding factors and potential reverse causality which is inherent in observational studies. MATERIALS AND METHODS: We performed a Mendelian randomization (MR) …

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Neurological and metabolic related pathophysiologies and treatment of comorbid diabetes with depression

Sixin Li, Dong Yang, Chao Zhou, Lu Chen et autres

BACKGROUND: The comorbidity between diabetes mellitus and depression was revealed, and diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the leading causes of disability-adjusted life-years. Insulin resistance, which is common in diabetes mellitus, has increased the risk of …

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Suicidal ideation in Chinese patients with chronic schizophrenia: prevalence, clinical correlates, and relationship with alexithymia

Yanan Zhou, Pu Peng, Ning Yuan, Yifan Xiong et autres

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Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model

Hui Cao, Yang Dong, Kechao Nie, Ruoheng Lin et autres

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Prevalence of non-alcoholic fatty liver disease in pediatric mental disorder inpatients: a tertiary mental health referral hospital study

Lini Liu, Rongrong Tan, Zheng‐Hua Fang, Li Li et autres

BACKGROUND AND AIM: Studies have revealed a high prevalence of non-alcoholic fatty liver disease (NAFLD) among adult patients with mental disorders, as well as its associate risk factors, however little is known about these in pediatric population. The aim of the present …

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Autologous esophageal mucosa transplantation to prevent esophageal stricture after endoscopic submucosal dissection: promising, but too early to draw a conclusion

Lini Liu, Hongping Wei, Jinhua Fu

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