Accès ouvert
2026
preprint
OpenAlex
Joseph D. Fernandes, Erin Bresnahan, Hillary Zawada, Joshua D. Ginzel et autres
Naturally occurring isoforms of the proto-oncogene Erb-B2 Receptor Tyrosine Kinase 2 (ERBB2, HER2) incite unique pathways of tumor progression in mouse models of breast cancer. Although each isoform has been shown to progress to metastasis, the N-terminally truncated isoform (p95) was previously …
us
(code pays fourni par la source)
2025
article
OpenAlex
Fulton Shannon, Chris Puli'uvea, Jasmine Tan, Rinki Murphy et autres
AIMS: The primary objective of this study was to explore type 2 diabetes (T2D) awareness, knowledge, attitudes and risk factors among youth in Auckland. METHODS: We undertook convenience sampling of participants aged 16-25 years of Pacific and Māori descent recruited from South, …
nz
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Zanetta L L Toomata, Yannan Jiang, Rui Qian Yeu, Rebecca Brandon et autres
Background/Objectives: This subgroup analysis of a randomised, open-label, two-period crossover trial in Aotearoa New Zealand (February 2019 to March 2020) assessed whether the glucose-lowering effects of vildagliptin, vs pioglitazone varied by the CREBRF (p.Arg457Gln) rs373863828 genotype. Methods: Adults with type 2 diabetes …
nz, pk, us, ca
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Jayne Doherty, C. Hurley, Parker Girod, Janet L. Peacock et autres
Abstract Background The British Society of Gastroenterology recommend the use of structured transition programmes to improve control of chronic GI disease in adolescents. Although research is limited structured transition programmes have been shown to improve disease outcomes in IBD {1}. Methods We …
ie, us
(code pays fourni par la source)
Accès ouvert
2025
conference-abstract
OpenAlex
M Nwaezeigwe, M Hanley, Krish Lakshman, Juliette Sheridan et autres
Abstract Background Sustainability of IBD care has been identified as a key priority for the coming years by ECCO as part of the REACH strategy. Additionally, the Irish Health Service Climate Action Strategy aims to achieve net-zero emissions by 2050 and provide …
ie
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Accès ouvert
2024
article
OpenAlex
Ry Y. Tweedie‐Cullen, Yannan Jiang, Rebecca Brandon, Audrey Tay et autres
AIMS: To assess whether diabetes treatment satisfaction differs by ethnicity among participants with insufficient glycaemic control of type 2 diabetes mellitus in a clinical trial involving additional oral diabetes medications. Patient satisfaction is used as an indicator of healthcare quality. However, data …
nz, us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Rebecca Brandon, Yannan Jiang, Rui Qian Yeu, Ry Y. Tweedie‐Cullen et autres
Background: Understanding which group of patients with type 2 diabetes will have the most glucose lowering response to certain medications (which target different aspects of glucose metabolism) is the first step in precision medicine. Aims: We hypothesized that people with type 2 …
nz, us
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
George A. Diaz, Alyssa Christensen, Tobias Pusch, Delaney Goulet et autres
BACKGROUND: The impact of remdesivir (RDV) on mortality rates in coronavirus disease 2019 (COVID-19) is controversial, and the mortality effect in subgroups of baseline disease severity has been incompletely explored. The purpose of this study was to assess the association of RDV …
us
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Accès ouvert
2021
article
OpenAlex
Tian Cooke, Fifita McCready, Glenn Doherty, Tim Cundy
INTRODUCTION Macroalbuminuria in people with type 2 diabetes is common among Pasifika peoples and is associated with end-stage kidney disease and major cardiovascular disease. AIM In a primary care practice catering for Pasifika people, to determine the time after first recognition of …
nz, au
(code pays fourni par la source)
2021
conference-paper
OpenAlex
Eabha Ring, Caroline Conlon, H Kerr, John O’Grady et autres
Aims The Irish National BowelScreen programme paused activities in March 2020 to prioritise the emergency response to the SARS-CoV-2 pandemic. As a result, patients with positive fecal immunochemical test (FIT) results that had already been returned, experienced delays in time to colonoscopy. …
ie
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Accès ouvert
2020
article
OpenAlex
Rui Qian Yeu, Rebecca Brandon, Yannan Jiang, Dale Griffiths et autres
INTRODUCTION: There is emerging evidence for stratified glucose-lowering responses to certain oral medications for type 2 diabetes (T2D) by individual characteristics. The objective of this study was to test whether glycaemic response to representative treatments of dipeptidyl peptidase-4 inhibitors (vildagliptin) and thiazolidinediones …
nz
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Accès ouvert
2008
article
OpenAlex
Celia M. Lescano, Christopher Houck, Larry K. Brown, Glenn Doherty et autres
OBJECTIVES: We sought to learn what factors are associated with anal intercourse among adolescents and young adults. We examined demographic, behavioral, relationship context, attitudinal, substance use, and mental health correlates of recent heterosexual anal intercourse among adolescents and young adults who reported …
us
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