Charmagne Beckett

Lung Function in Young, Active Duty U.S. Marines After SARS-CoV-2 Infection

Lindsey J White, Jeffrey D. Biberston, Silvia J. Jakubski, David A. Boulifard et autres

INTRODUCTION: Post-acute sequelae of SARS-CoV-2 (PASC) or long COVID may lead to an array of adverse health outcomes in young, otherwise healthy adults, potentially limiting warfighter readiness. This study assessed pulmonary function in Marines to evaluate associations between acute and chronic symptoms …

us, gb (code pays fourni par la source)

Safety and Immunogenicity of a Trivalent Salmonella Conjugate Vaccine to S. Typhi, S. Typhimurium, and S. Enteritidis

Wilbur H. Chen, Charmagne Beckett, Mohamed Al-Ibrahim, Reva Datar et autres

BACKGROUND: Invasive disease caused by typhoid and nontyphoidal Salmonella (NTS) is a threat confronting young children in sub-Saharan Africa. We are developing a trivalent Salmonella conjugate vaccine (TSCV) consisting of typhoid Vi conjugate and core-O-polysaccharide conjugates from 2 invasive NTS serovars (S. …

us, gb, in (code pays fourni par la source)

Artificial Intelligence Guided Nonexpert Echocardiogram in the COVID ‐19 Health Action Response in Marines 2.0 Study

Andrew G. Letizia, Elizabeth Cooper, Charmagne Beckett, Chad K. Porter et autres

ABSTRACT Purpose Echocardiography is a widely utilized cardiac imaging modality, but accessibility can be limited by cost and lack of skilled sonographers. We demonstrate the use of point‐of‐care ultrasound (POCUS) with an embedded deep learning algorithm to guide novice users in obtaining …

us, sg, cn, gb (code pays fourni par la source)

Clinical and functional assessment of SARS-CoV-2 sequelae among young marines – a panel study

Chad K. Porter, Charmagne Beckett, Elizabeth Cooper, Lindsey White et autres

Background: Long-term SARS-CoV-2 adverse health outcomes are of significant concern, especially among young adults with the potential for the greatest long-term morbidity. We sought to assess and characterize these outcomes in a cohort of Marines. Methods: We used a cohort of US …

us, se (code pays fourni par la source)

Sepsis endotypes identified by host gene expression across global cohorts

Josh Chenoweth, Joost Brandsma, Deborah A. Striegel, Pavol Genzor et autres

BACKGROUND: Sepsis from infection is a global health priority and clinical trials have failed to deliver effective therapeutic interventions. To address complicating heterogeneity in sepsis pathobiology, and improve outcomes, promising precision medicine approaches are helping identify disease endotypes, however, they require a …

us, Ghana (code pays fourni par la source)

Lung Function in Active-duty Marines After COVID-19 Infection

Lindsey White, J. Biberston, Ellen Cooper, Charmagne Beckett et autres

us (code pays fourni par la source)

Clinical and Functional Assessment of SARS-CoV-2 Sequelae Among Young Marines

Chad K. Porter, Charmagne Beckett, Elizabeth Cooper, Lindsey White et autres

Risk of sexually transmitted infections among U.S. military service members in the setting of HIV pre-exposure prophylaxis use

Jason M Blaylock, Evan Ewers, Elizabeth J. Bianchi, David B. King et autres

BACKGROUND: The evidence for an increased incidence of sexually transmitted infections (STIs) among patients utilizing HIV pre-exposure prophylaxis (PrEP) has been inconsistent. We assessed the risk of incident STI while on PrEP compared to periods off PrEP among military service members starting …

us (code pays fourni par la source)

Long-term Mortality Among Hospitalized Adults with Sepsis in Uganda: a Prospective Cohort Study

Paul W. Blair, Stephen Okello, Abdullah Wailagala, Rodgers R Ayebare et autres

Abstract Background Twelve-month mortality in sepsis survivors has not been previously characterized in sub-Saharan Africa. Methods Hospitalized adults with ≥ 2 modified systemic inflammatory response syndrome (SIRS) criteria (temperature < 36°C or > 38°C, heart rate ≥ 90 beats per minute, or …

us, Ouganda (code pays fourni par la source)

Screening tools for predicting mortality of adults with suspected sepsis: an international sepsis cohort validation study

Paul W. Blair, Rittal Mehta, Chris Oppong, Tin Som et autres

OBJECTIVES: We evaluated the performance of commonly used sepsis screening tools across prospective sepsis cohorts in the USA, Cambodia and Ghana. DESIGN: Prospective cohort studies. SETTING AND PARTICIPANTS: From 2014 to 2021, participants with two or more SIRS (Systemic Inflammatory Response Syndrome) …

us, Ghana, kh (code pays fourni par la source)

Causes and Risk of Long-Term Sepsis Mortality in Uganda: A Prospective Cohort Study

Paul W. Blair, Stephen Okello, Abdullah Wailagala, Rodgers R Ayebare et autres

us, Ouganda (code pays fourni par la source)

1169. Derivation And Validation of an International Clinical Prognostication Model for 28-day Sepsis Mortality.

Paul W. Blair, Rittal Mehta, Tin Som, Stephen Okello et autres

Abstract Background Survival prediction models have largely been derived and validated only in high-resource Western countries or in single center studies. We sought to create a prediction model for 28-day mortality using laboratory and physiologic parameters from 3 international sepsis cohorts and …

us, jp, Ouganda, kh, Ghana (code pays fourni par la source)