Xuejuan Ma

Long-term benefits of single left ventricular pacing based on rate-adaptive atrioventricular delay algorithm in cardiac resynchronization therapy

Xuejuan Ma, Lulu Zhao, Guihu Sun, Ling Zhao et autres

Background Current guidelines lack long-term evidence comparing single left ventricular pacing (LUVP) with standard biventricular pacing (BVP) in cardiac resynchronization therapy (CRT). This study evaluates the clinical superiority of rate-adaptive atrioventricular delay (RAAVD) algorithm-guided LUVP over BVP. Methods In this retrospective cohort …

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Mitophagy-associated biomarkers and macrophage involvement in pulmonary arterial hypertension: identification and functional implications

Xiaoyu Zhang, Liming Cheng, Jiahui Xie, Xuejuan Ma et autres

Background Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by pulmonary vascular remodeling and mitochondrial dysfunction. Recent studies have implicated impaired mitophagy in the pathogenesis of PAH; however, the underlying mechanisms and associated biomarkers remain insufficiently defined. This study used an …

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Multi-omics reveals the mechanism of vagus nerve stimulation in the treatment of chronic congestive heart failure

Yuchi Hu, Songyuan Dai, Liling Chen, Xuejuan Ma et autres

The potential benefits and underlying mechanisms of Vagus Nerve Stimulation (VNS) in the treatment of Chronic Congestive Heart Failure (CHF) remain insufficiently elucidated. Therefore, this study aims to investigate the therapeutic potential and mechanisms of VNS in treating CHF. In this study, …

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Monitoring Values of Routine Echocardiography and Two-dimensional Speckle Tracking Imaging in Cardiotoxicity Caused by Treatment of Breast Carcinoma with Anthracyclines

Wenjuan Song, Xuejuan Ma, Yue Sun, Liping Liu et autres

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Two-dimensional Speckle Tracking Imaging in Cardiotoxicity Caused by Treatment of Breast Carcinoma with Anthracyclines

Wenjuan Song, Xuejuan Ma, Yue Sun, Liping Liu et autres

Objective: This research was conducted to investigate the monitoring values of routine echocardiography (ECG) and two-dimensional speckle tracking imaging (2D-STI) in cardiotoxicity caused by the treatment of breast carcinoma with anthracyclines (ANTH).Methods: 100 patients with breast carcinoma were selected and enrolled into …

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Principle and design of clinical efficacy observation of extracorporeal cardiac shock wave therapy for patients with myocardial ischemia-reperfusion injury: A prospective randomized controlled trial protocol

Xianbin Li, Chaoyue Zhang, Changzhi Liu, Yiming Ma et autres

BACKGROUND: Acute ST-segment elevation myocardial infarction (STEMI) remains a serious life threatening event with a poor prognosis due to myocardial ischemia/reperfusion injury despite coronary revascularization. Extracorporeal cardiac shock wave (ECSW) is a safe, effective and non-invasive new method for the treatment of …

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Dumbbell in the atrium: A rare case report of biatrial myxoma that crosses atrial septum diagnosed by multimodal echocardiography

Wenjuan Song, Yu Wang, Xuejuan Ma, Liping Liu et autres

We reported a very rare case, a 59-year-old female whose heart myxoma was present in both atrium, the mass in biatrial was connected to each other at the oval foramen, resembling "dumbbell-like." By means of multimodality echocardiography techniques such as transthoracic echocardiography …

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Cardiac Shock Wave Therapy Improves Ventricular Function by Relieving Fibrosis Through PI3K/Akt Signaling Pathway: Evidence From a Rat Model of Post-infarction Heart Failure

Luqiao Wang, Xin Tian, Yuting Cao, Xuejuan Ma et autres

Objection: Cumulative studies have identified the effectiveness of cardiac shock wave therapy (CSWT) in treating heart failure after acute myocardial infarction (AMI), but little have been discussed with regard to the beneficial effects of CSWT on anti-fibrosis along with the underlying mechanism. …

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Unexpected echocardiographic findings：Accessory Mitral Valve Tissue in Adults

Ying Rao, Yu Wang, Wei Chen, Wenjuan Song et autres

Accessory mitral valve tissue (AMVT) is a rare congenital cardiac anomaly, which is associated with other congenital heart diseases. It is diagnosed in neonates or childhood and rarely in adulthood. Nevertheless, AMVT is an incidental finding or described as isolated. Echocardiography, especially …

Typical ST-segment elevation myocardial infarction with normal coronary arteries: a case report

Ying Rao, Yu Wang, Huang Sun, Wei Chen et autres

Myocardial infarction with nonobstructive coronary arteries (MINOCA) is a potentially multipathogenic syndrome that affects a subgroup of patients who present with acute myocardial infarction yet have no significant coronary artery disease on angiography. We herein describe a 71-year-old man with typical angina …

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[Role of PI3K/Akt signaling pathway in ischemic rats underwent cardiac shock waves therapy].

Leilei Shang, Zhen Su, Xuejuan Ma, Yanqiong Wang et autres

CSWT improves cardiac function and inhibits cardiomyocyte apoptosis through PI3K/Akt signaling pathways in this rat HF model.

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Myocardial Microcirculation and Systolic Function in Patients with Ischemia and Nonobstructive Coronary Artery Diseases by Myocardial Contrast Echocardiography and Speckle Tracking Imaging

Ying Rao, Yu Wang, Wenjuan Song, Xuejuan Ma et autres