Accès ouvert
2026
article
OpenAlex
Deborah K. Erhart, Luisa T. Balz, Roland Opfer, Lothar Spies et autres
BACKGROUND: Fatigue and cognitive impairment are common in multiple sclerosis (MS) affecting up to 95% and 65% of the patients, respectively. Only little is known about the interplay of different volumetric magnetic resonance imaging (MRI) parameters, the serum biomarkers neurofilament light chain …
de
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Accès ouvert
2026
other
OpenAlex
Deborah K. Erhart, Luisa T. Balz, Roland Opfer, Lothar Spies et autres
Abstract Background Fatigue and cognitive impairment are common in multiple sclerosis (MS) affecting up to 95% and 65% of the patients, respectively. Only little is known about the interplay of different volumetric magnetic resonance imaging (MRI) parameters, the serum biomarkers neurofilament light …
de
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Deborah K. Erhart, Luisa T. Balz, Roland Opfer, Lothar Spies et autres
Supplementary Material 1.
de
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Accès ouvert
2026
article
OpenAlex
Deborah K. Erhart, Luisa T. Balz, Roland Opfer, Lothar Spies et autres
Supplementary Material 1.
de
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Accès ouvert
2025
article
OpenAlex
Luisa T. Balz, Ingo Uttner, Daniela Taranu, Deborah K. Erhart et autres
Background/Objectives: Cognitive impairment is one of the most common and debilitating clinical features of Multiple Sclerosis (MS). Neuropsychological assessment, however, is time-consuming and requires personal resources, so, due to limited resources in daily clinical practice, information on cognitive profiles is often lacking, …
de, us
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Accès ouvert
2025
article
OpenAlex
Luisa T. Balz, Ingo Uttner, Jochen H. Weishaupt, Albert C. Ludolph et autres
Background/Objectives: Multiple sclerosis (MS) is a complex neurological disease that is associated with a broad spectrum of physical and psychological symptoms. Psychosocial adjustment (PSA) refers to the ability to cope with these challenges, which influence quality of life (QoL) and depressiveness in …
de
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Accès ouvert
2025
article
OpenAlex
Ahmed Abdelhak, Franziska Bachhuber, Kiarra Ning, Pascal Benkert et autres
BACKGROUND AND OBJECTIVES: Biologically informative markers like glial fibrillary acidic protein (GFAP) and neurofilament light chain (NfL) may help predict confirmed disability worsening (CDW) in multiple sclerosis (MS). However, data on the prognostic value of their blood concentrations in progressive MS (PMS) …
us, de, ch, sk, ca, se, it, es, nl, dk, at, fr, pl, gr
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Accès ouvert
2025
article
OpenAlex
Daniela Taranu, Luisa T. Balz, Jill Holbrook, Visal Tumani et autres
BACKGROUND: Multiple sclerosis (MS) subtypes-relapsing-remitting (RRMS), secondary-progressive (SPMS), and primary-progressive (PPMS) - have been associated with distinct cognitive impairment profiles, with progressive subtypes, in contrast to RRMS, showing additional deficits in more widespread domains. Research has largely focused on RRMS, leaving SPMS …
de, us
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Accès ouvert
2025
article
OpenAlex
Ioannis Vardakas, Johannes Dorst, André Huss, Benjamin Mayer et autres
Background: Evidence on neurochemical mechanisms underlying response to apheresis in steroid-refractory Multiple Sclerosis (MS) attacks is limited. Objective: To examine the effect of immunoadsorption (IA) versus plasma exchange (PLEX) on serum immunological parameters [IgG, IgA, IgM, kappa- and lambda-immunoglobulin free light chains …
de, sa
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Accès ouvert
2025
article
OpenAlex
Daniela Taranu, Hayrettin Tumani, Visal Tumani, Patrick Fissler
Behavioral activation therapy (BAT) was initially developed to treat depression and was subsequently extended as a transdiagnostic therapy for other psychiatric and neurocognitive disorders. However, research on its impact in people with multiple sclerosis (MS) is lacking. We suggest that MS-adapted BAT …
de, ch
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Accès ouvert
2025
article
OpenAlex
Stefan Buchka, Alexander Hapfelmeier, Jan S. Kirschke, Verena Steuerwald et autres
Background: The course of relapsing-remitting multiple sclerosis (RRMS), frequently preceded by the clinically isolated syndrome (CIS), is variable and challenging to predict. Given many treatment options available, prognostic algorithms are gaining importance in informing initial treatment decisions. However, to date, only a …
nl, de
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Accès ouvert
2024
article
OpenAlex
Ioannis Vardakas, Johannes Dorst, André Huss, Benjamin Mayer et autres
BACKGROUND AND PURPOSE: The predictive value of serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein (sGFAP) for apheresis outcome in steroid-refractory multiple sclerosis (MS) relapse has not yet been evaluated. METHODS: We used pre- and postapheresis serum samples from …
de
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