Accès ouvert
2024
article
OpenAlex
Cody A. Ramirez, Michelle Becker‐Hapak, Kartik Singhal, David A. Russler‐Germain et autres
ABSTRACT: Personalized cancer vaccines designed to target neoantigens represent a promising new treatment paradigm in oncology. In contrast to classical idiotype vaccines, we hypothesized that "polyvalent" vaccines could be engineered for the personalized treatment of follicular lymphoma (FL) using neoantigen discovery by …
us
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Manish A. Shah, Sandipto Sarkar, Daria Melikhova, Prashant V. Thakkar et autres
us, fr
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Katherine Rae Antel, Aleksander Nesmelov, Meng‐Xuan Wu, Charlotte Slome et autres
Abstract Lymphoma, a leading cancer cause of death among people living with HIV (PLHIV) globally, poses a pressing public health challenge in Sub-Saharan Africa (SSA), the epicentre of the HIV epidemic. Despite its prevalence, the genetic underpinnings of lymphoma in Black Africans …
us, Afrique du Sud
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Alexander Ling, Isaac H. Solomon, Ana Montalvo Landivar, Hiroshi Nakashima et autres
Abstract Immunotherapy failures can result from the highly suppressive tumour microenvironment that characterizes aggressive forms of cancer such as recurrent glioblastoma (rGBM) 1,2 . Here we report the results of a first-in-human phase I trial in 41 patients with rGBM who were …
us, il
(code pays fourni par la source)
Accès ouvert
2023
other
OpenAlex
Nikita Kotlov, Alexander Bagaev, Maria Victoria Revuelta, Jude M. Phillip et autres
Abstract Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous disease. Transcriptomic and genetic characterization of DLBCL has increased the understanding of its intrinsic pathogenesis and provided potential therapeutic targets. However, the role of the microenvironment in DLBCL biology remains …
Accès ouvert
2023
supplementary-materials
OpenAlex
Nikita Kotlov, Alexander Bagaev, Maria Victoria Revuelta, Jude M. Phillip et autres
Supplementary Figures
Accès ouvert
2023
supplementary-materials
OpenAlex
Nikita Kotlov, Alexander Bagaev, Maria Victoria Revuelta, Jude M. Phillip et autres
Supplementary Figures
Accès ouvert
2023
other
OpenAlex
Nikita Kotlov, Alexander Bagaev, Maria Victoria Revuelta, Jude M. Phillip et autres
Abstract Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous disease. Transcriptomic and genetic characterization of DLBCL has increased the understanding of its intrinsic pathogenesis and provided potential therapeutic targets. However, the role of the microenvironment in DLBCL biology remains …
Accès ouvert
2023
supplementary-materials
OpenAlex
Nikita Kotlov, Alexander Bagaev, Maria Victoria Revuelta, Jude M. Phillip et autres
Supplementary Tables
Accès ouvert
2023
supplementary-materials
OpenAlex
Nikita Kotlov, Alexander Bagaev, Maria Victoria Revuelta, Jude M. Phillip et autres
Supplementary Tables
Accès ouvert
2023
article
OpenAlex
Susan Raju Paul, Ivan Valiev, Skylar Korek, Vladimir Zyrin et autres
Abstract Lung cancer is the leading cause of cancer‐related deaths worldwide. Surgery and chemoradiation are the standard of care in early stages of non‐small cell lung cancer (NSCLC), while immunotherapy is the standard of care in late‐stage NSCLC. The immune composition of …
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Subhajit Ghosh, Jiayi Huang, Matthew J. Inkman, Jin Zhang et autres
Severe and prolonged lymphopenia frequently occurs in patients with glioblastoma after standard chemoradiotherapy and has been associated with worse survival, but its underlying biological mechanism is not well understood. To address this, we performed a correlative study in which we collected and …
us
(code pays fourni par la source)