Margarita Trejo

Editorial Expression of Concern: Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin

Kiren K. Ubhi, Edward M. Rockenstein, Edith Doppler, Michael Mante et autres

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Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

Changyoun Kim, Edward M. Rockenstein, Brian J. Spencer, Hyung-Koo Kim et autres

Retraction Note: Brain-derived exosomes from dementia with lewy bodies propagate α-synuclein pathology

Jennifer Ngolab, Ivy Trinh, Edward M. Rockenstein, Michael Mante et autres

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Retraction Note: Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure

Edward M. Rockenstein, Kiren K. Ubhi, Margarita Trejo, Michael Mante et autres

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Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

Changyoun Kim, Edward M. Rockenstein, Brian J. Spencer, Hyung-Koo Kim et autres

Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Jennifer Ngolab, Ivy Trinh, Edward M. Rockenstein, Michael Mante et autres

An amendment to this paper has been published and can be accessed via the original article.

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The Victimization of the Misconceived: The Mentally Ill in the Criminal Justice System

Margarita Trejo

It is unfortunate to say that the number of people who suffer from a serious mental illness has been drastically increasing in the criminal justice system since the late 1960s. This drastic change has captivated the minds of the public, forced them …

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MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy

Elvira Valera, Brian J. Spencer, Jennifer Mott, Margarita Trejo et autres

Synucleinopathies, neurodegenerative disorders with alpha-synuclein (α-syn) accumulation, are the second leading cause of neurodegeneration in the elderly, however no effective disease-modifying alternatives exist for these diseases. Multiple system atrophy (MSA) is a fatal synucleinopathy characterized by the accumulation of toxic aggregates of …

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Human Immunodeficiency Virus Promotes Mitochondrial Toxicity

Summer J. Rozzi, Valeria Avdoshina, Jerel Adam Fields, Margarita Trejo et autres

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Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Patrick T. Reilly, Charisse N. Winston, Kelsey R Baron, Margarita Trejo et autres

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RETRACTED ARTICLE: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Jennifer Ngolab, Ivy Trinh, Edward M. Rockenstein, Michael Mante et autres

Abstract Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in extracellular vesicles called exosomes. Whether exosomes found in DLB patients can transmit pathology is not clear. In …

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P4‐289: Novel Human Neuronal TAU Model Exhibiting Neurofibrillary Tangles and Transcellular Propagation

Shauna H. Yuan, Patrick T. Reilly, Kelsey R Baron, Margarita Trejo et autres

Tauopathy is defined as a group of neurodegenerative diseases, including Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy, in which the misfolded tau proteins form neurofibrillary tangles (NFT). A better understanding of the mechanisms of tau misfolding and aggregation, and their pathological …

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