2006
article
OpenAlex
Andreas Holstein, A. Plaschke, Yvonne Böttcher, Michael Stümvoll et autres
Impaired hypoglycemia awareness affects approximately 25% of all patients with type 1 diabetes (T1DM). Duration of diabetes and tight glycemic control represent main risk factors of impaired hypoglycemia awareness. However, even among patients with good glycemic control and longstanding T1DM, awareness of …
de
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2005
article
OpenAlex
A. Holstein, JOERG BURMEISTER, A. Plaschke, DIRK ROSEMEIER et autres
OBJECTIVE: The etiology of microscopic colitis is unclear; an autoimmune response and pharmacological induction have been proposed as possible mechanisms. We conducted a multicentre cross-sectional study to compare the antibody profiles of patients with collagenous and lymphocytic colitis with those of a …
de
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2005
article
OpenAlex
Andreas Holstein, A. Plaschke, Michael Stümvoll, Péter Kovács
de
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2005
article
OpenAlex
Andreas Holstein, A. Plaschke, Peter Lohse, E.‐H. Egberts
Severe hyperbilirubinemia in a pregnant mother suffering from Crigler-Najjar syndrome type II is a threat to the unborn child and may result in brain injury. We report the case of a Gly71-->Arg/Tyr486-->Asp homozygous mother of East Asian descent, who was treated with …
de
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Accès ouvert
2005
article
OpenAlex
Andreas Holstein, A. Plaschke, Magdalena Ptak, E.‐H. Egberts et autres
AIMS: The genetically polymorphic cytochrome P450 (CYP) enzyme CYP2C9 metabolizes most sulphonylurea oral hypoglycaemic agents. The aim of this study was to test the hypothesis that individuals with genotypes predicting low CYP2C9 activity may be at a higher risk of severe drug-associated …
de
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2004
article
OpenAlex
Andreas Holstein, C. Hammer, A. Plaschke, Magdalena Ptak et autres
AIM: To determine the counterregulatory hormonal responses to severe hypoglycaemia (SH) in type 1 versus insulin-treated type 2 diabetic patients under everyday conditions. METHODS: Counterregulatory hormones were determined in 28 consecutive type 1 and thirteen insulin-treated type 2 diabetic patients (age 54 …
de
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2004
article
OpenAlex
Andreas Holstein, A. Plaschke, Magdalena Ptak, E.‐H. Egberts et autres
de
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Accès ouvert
2004
article
OpenAlex
M. Veitenhansl, K. Stegner, F. X. Hierl, C. Dieterle et autres
2003
article
OpenAlex
Andreas Holstein, A. Plaschke, C. Hammer, Magdalena Ptak et autres
de
(code pays fourni par la source)
2003
article
OpenAlex
Andreas Holstein, A. Plaschke, E.‐H. Egberts
AIM: To determine the clinical characteristics of severe hypoglycaemia (SH) in a nonselected German population. SH was defined as an event requiring intravenous glucose or glucagon injection. METHODS: The prospective population-based study screened sensitively for SH in a region with 200,000 inhabitants …
de
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Accès ouvert
2003
article
OpenAlex
Andreas Holstein, A. Plaschke, E.‐H. Egberts
Technical failure in photographic screening for diabetic retinopathyDiabetic retinopathy is the largest single cause of registered blindness among people of working age.At any time, 10% of the diabetic population may have retinopathy requiring ophthalmological follow-up or treatment [1].The two main approaches to …
de
(code pays fourni par la source)
2003
article
OpenAlex
Andreas Holstein, A. Plaschke, C. Hammer, E.‐H. Egberts
de
(code pays fourni par la source)