Yuval Ishay

The Management of Irritable Bowel Syndrome

Fahmi Shibli, Roy Dekel, Ron Yishai, Joseph Lysy et autres

Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction with symptoms including abdominal pain associated with a change in stool form or frequency. IBS global prevalence is around 4% and its impact on patient's quality of life and social functioning is …

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Mo1890 IMPACT OF ELEXACAFTOR/TEZACAFTOR/IVACAFTOR (ETI) ON GASTROINTESTINAL INFLAMMATION, MOTILITY, AND SYMPTOMS IN CYSTIC FIBROSIS: A MULTICENTER PROSPECTIVE STUDY

Michael Wilschanski, Liron Birimberg‐Schwartz, Jennifer Hudson, Josie M. van Dorst et autres

Mo1890 IMPACT OF ELEXACAFTOR/TEZACAFTOR/IVACAFTOR (ETI) ON GASTROINTESTINAL INFLAMMATION, MOTILITY, AND SYMPTOMS IN CYSTIC FIBROSIS: A MULTICENTER PROSPECTIVE STUDY

Michael Wilschanski, Liron Birimberg‐Schwartz, Jennifer Hudson, Josie M. van Dorst et autres

Sleeve gastrectomy reveals the plasticity of the human gastric epithelium

Amit Elad, Botros Moalem, Dana Sender, Aya Bardugo et autres

Gastrin is secreted following a rise in gastric pH, leading to gastric acid secretion. Sleeve gastrectomy (SG), a bariatric surgery where 80% of the gastric corpus is excised, presents a challenge for gastric pH homeostasis. Using histology, and single-cell RNA sequencing of …

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Gastrointestinal and Hepatic Manifestations of Systemic Amyloidosis

Yuval Ishay, Tiberiu Hershcovici

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Investigating the Relationship between Chronic Liver Cirrhosis and Parkinsonism: A Comparative Analysis and a Suggested Diagnostic Scheme

Tal Sigawi, Omer Hamtzany, Noa Hurvitz, Yuval Ishay et autres

Aim: Neurological manifestations are common in patients with chronic liver diseases. This study aimed to depict the association between liver cirrhosis and Parkinson’s disease (PD) and propose a clinically relevant diagnostic scheme. Methods: We examined patients’ medical records with PD and chronic …

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Oral Insulin Alleviates Liver Fibrosis and Reduces Liver Steatosis in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes: Results of Phase II Randomized, Placebo-controlled Feasibility Clinical Trial

Yuval Ishay, Joel Neutel, Yotam Kolben, Ram Gelman et autres

Background and Aims: Metabolic dysfunction-associated steatohepatitis is an advanced form of nonalcoholic fatty liver disease and a leading cause of end-stage liver disease and transplantation. Insulin resistance and inflammation underlie the pathogenesis of the disease. Methods: This double-blind, randomized, placebo-controlled, multicenter feasibility …

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Weaker SARS-CoV-2 vaccine responses in nonalcoholic fatty liver disease with advanced liver fibrosis

David Hakimian, Johnny Amer, Alaa Jammal, Asher Shafrir et autres

SARS-CoV-2 vaccine responses that could harbor potential risks to chronic liver diseased patients. To assess immune response following Pfizer's SARS-CoV-2 vaccine in patients with different liver fibrosis severities of nonalcoholic fatty liver disease (NAFLD). Clinical and histological (NAS-score and fibrosis stage) characteristics …

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98-OR: Oral Insulin Alleviates Liver Fibrosis and Reduces Fat in Patients with NASH and Type 2 Diabetes—Results of Phase II Clinical Trial

Yuval Ishay, Joel M. Neutel, Yotam Kolben, Ram Gelman et autres

NAFLD is the most common liver disorder in the USA. NASH is an advanced form of NAFLD and a leading cause of end-stage liver disease and indication for liver transplantation. Insulin resistance and inflammation underlie the pathogenesis of the disease. This double-blind, …

Serum Levels of Adropin Improve the Predictability of MELD and Child-Pugh Score in Cirrhosis: Results of Proof-of-Concept Clinical Trial

Yotam Kolben, Ariel Kenig, Asa Kessler, Yuval Ishay et autres

Adropin is a peptide that was suggested to have a role in cirrhosis. The present study aimed to determine the ability to use serum adropin levels to improve their prediction accuracy as an adjunct to the current scores. In a single-center, proof-of-concept …

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Oral ulcers, uveitis and thrombosis are looking for a diagnosis…

Esther Forkosh, Yuval Ishay, Asaf Schwartz, Aviv Talmon et autres

Case presentationChief symptoms A forty-year-old man came to the Emergency Department (ED) of our Medical Centre, because of fever, headache and weakness of two weeks duration.

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Autoimmune Diseases Induced or Exacerbated by COVID-19: A Single Center Experience

Yuval Ishay, Ariel Kenig, Limor Rubin, Oded Shamriz et autres

The association between infectious diseases and autoimmunity has long been reported. Specifically, during the coronavirus disease 2019 (COVID-19) pandemic, this relation was further emphasized. The interplay between the two disease processes remains interesting, yet incompletely defined. Herein, we report a case series …

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