Accès ouvert
2025
article
OpenAlex
Yufang Wang, Fang‐Wen Hu, Jinyong Ke
This study aimed at evaluating prognostic factors for survival and treatment response in patients with myelodysplastic syndromes (MDS) transforming to acute myeloid leukemia (AML). This retrospective study included 182 MDS patients treated at our hospital between January 2018 and January 2023, with …
cn
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Accès ouvert
2024
article
OpenAlex
Yang Yang, Jinyong Ke, Yang Cao, Yue Gao et autres
Sepsis-associated encephalopathy (SAE) is a disease characterized by neuroinflammation and cognitive dysfunction caused by systemic infection. Inflammation-induced microglial activation is closely associated with neuroinflammation in SAE. It is widely understood that melatonin has strong anti-inflammatory and immunomodulatory properties beneficial for sepsis-related brain …
cn
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Accès ouvert
2024
article
OpenAlex
Hongyu An, Shiming Chen, Xin Zhang, Shandong Ke et autres
OBJECTIVE: Plant homeodomain finger protein 19 (PHF19) regulates hematopoietic stem cell differentiation and promotes multiple myeloma (MM) progression. This study intended to explore the potency of PHF19 at baseline and post induction treatment in estimating treatment response to protease inhibitors and survival …
cn
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Accès ouvert
2022
article
OpenAlex
Jinyong Ke, Zhi‐Yong Liu, Yunhan Wang, Shiming Chen et autres
saponins (GpS) regulating mitochondrial autophagy and anti-inflammatory through Sirtuin 1 (Sirt1) pathway in systemic lupus erythematosus (SLE). JURKAT cells were cultured in vitro, RT-PCR and western blotting (WB) were utilized to identify the expression of related-proteins in Sirt1 pathway and global autophagy …
cn
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2017
article
OpenAlex
Jinyong Ke
目的 提高对小肠弥漫大B细胞淋巴瘤(DLBCL)颊部转移的认识。 方法 分析1例小肠DLBCL颊部转移患者的临床资料,复习相关文献并讨论其临床特征及诊疗方法。 结果 患者为男性,45岁,发现小肠恶性淋巴瘤8个月,左侧面颊部肿胀1周入院。左颊部肿物活组织检查病理结果倾向恶性淋巴瘤,给予CHOPE方案化疗1个周期后左颊部肿胀消失。 结论 小肠DLBCL伴颊部转移罕见,是一种高度侵袭性肿瘤,预后较差。颊部转移易被误诊为感染性疾病。组织学形态及免疫组织化学染色有助于明确诊断,手术切除后辅助化疗及放疗可能提高临床疗效。
cn
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2016
article
OpenAlex
Yalan Lu, Xin Zhang, Yufang Wang, Shandong Ke et autres
OBJECTIVE: To study the influence of leukodeplated blood transfusion on cellular immunity of patients with acute leuemia, so as to provide support for application of leuko-deplated blood transfusion in clinic. METHODS: A total of 100 AL patients from January 2012 to December …
cn
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