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Creatine kinase is an intracellular enzyme found abundantly in skeletal muscle, myocardium and brain. It is well known as a biomarker that increases following skeletal muscle damage and doctors instinctively associate it with myopathies. Serum creatine kinase is undoubtedly often raised in …
gb (code pays fourni par la source)
gb (code pays fourni par la source)
Jildou N. Dijkstra, Eline Boon, Nick Kruijt, Esther Brusse et autres
Muscle cramps are painful, sudden, involuntary muscle contractions that are generally self-limiting. They are often part of the spectrum of normal human physiology and can be associated with a wide range of acquired and inherited causes. Cramps are only infrequently due to …
nl, gb (code pays fourni par la source)
When asked to assess patients in an intensive care unit (ICU) who have respiratory muscle weakness, oropharyngeal weakness and a vulnerable airway, our immediate thought may be of Guillain-Barré syndrome or myasthenia gravis, but there are many other possible causes. For example, …
gb, us (code pays fourni par la source)
Janev Fehmi, Alexander J. Davies, Jon Walters, Timothy Lavin et autres
OBJECTIVES: We aimed to define the clinical and serological characteristics of pan-neurofascin antibody-positive patients. METHODS: We tested serum from patients with suspected immune-mediated neuropathies for antibodies directed against nodal/paranodal protein antigens using a live cell-based assay and solid-phase platform. The clinical and …
gb, ie (code pays fourni par la source)
Skeletal muscle biopsy remains an important investigative tool in the diagnosis of a variety of muscle disorders. Traditionally, someone with a limb-girdle muscle weakness, myopathic changes on electrophysiology and raised serum creatine kinase (CK) would have a muscle biopsy. However, we are …
gb (code pays fourni par la source)
Anne Berit Petersen, Holly Stewart, Jon Walters, Maya Vijayaraghavan
us (code pays fourni par la source)
Anne Berit Petersen, Holly Stewart, Jon Walters, Maya Vijayaraghavan
us (code pays fourni par la source)
The physical examination always begins with a thorough inspection and patients with potential neuromuscular weakness are no exception. One question neurologists routinely address during this early part of the assessment is whether or not there is muscle enlargement. This finding may reflect …
gb (code pays fourni par la source)
Besa Ziso, Timothy L. Williams, Jon Walters, Stephan R. Jaiser et autres
Introduction Facial onset sensory motor neuronopathy (FOSMN) is a rare, slowly progressive bulbar onset motor and sensory neuronopathy. Described only in 2006, it is still under–recognised with fewer than 20 cases reported in world literature. Although there are marked similarities to classical …
gb (code pays fourni par la source)
FOSMN is heralded by facial sensory loss with subsequent sensory and motor loss spreading caudally. Few cases have been described in the literature but a single case with upper motor neurone features drew parallels to motor neurone disease (MND). A woman with …
gb (code pays fourni par la source)
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