Donghai Xia

Streamlined strategy for discovering active compounds for nephrolithiasis treatment from herbal medicines using the fruit fly model

Yunuo Ren, Wen Jie Zhang, Youxin Li, Dekun Wang et autres

ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Chinese medicines (TCMs) show promise for treating nephrolithiasis (kidney stones) with fewer adverse effects. However, identifying the key active compounds and understanding the therapeutic mechanisms of these herbs is challenging due to their complex compositions. Utilizing appropriate animal models …

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Identification of a Novel NPC1L1 Inhibitor from Danshen and Its Role in Nonalcoholic Fatty Liver Disease

Donghai Xia, Xuan Jiang, Xiaomin Xie, Han Zhou et autres

Danshen, a well-known traditional Chinese medicine (TCM), has gained increasing attention for its protective effects on nonalcoholic fatty liver disease (NAFLD). However, the molecular mechanisms underlying these effects remain to be elucidated. Niemann-Pick C1-like 1 (NPC1L1), a key transporter mediating intestinal cholesterol …

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Cryptotanshinone Alleviates Nonalcoholic Fatty Liver Disease by Inhibiting NPC1L1-Mediated Intestinal Cholesterol Absorption

Donghai Xia, Xuan Jiang, Xiaomin Xie, Dongping Yu et autres

Danshen, a well-known traditional Chinese medicine (TCM), has gained increasing attention due to the protective effects on nonalcoholic fatty liver disease (NAFLD). However, the molecular basis and working mechanism remain to be elucidated. Niemann-Pick C1-like 1 (NPC1L1) is the crucial target mediating …

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[Development progress of stationary phase for supercritical fluid chromatography and related application in natural products].

Gaowa Jin, Dongping Yu, Donghai Xia, Jing Feng et autres

, the most widely employed supercritical fluid to date, presents moderate critical conditions and, more importantly, is miscible with a variety of polar organic solvents, including small quantities of water. In comparison with the mobile phases used in normal-phase liquid chromatography (NPLC) …

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A Gas Concentration Detection Algorithm Based on Biochemistry Molecular Relaxation Models

Ming Zhu, Shu Wang, Donghai Xia

In this paper, we establish some multi-dimensional biochemistry molecular relaxation recognition pattern models for the concentrations of gas mixture constituents versus effective relaxation frequency, multi-relaxation absorption, and acoustic velocity, respectively. Based on these match models and measured parameters, we propose a biochemistry …

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A Method of Gas Source Orientation Recognition for Bioenergy Detection

Donghai Xia, Shu Wang, Ming Zhu, Hui Tang

For realizing the behavior rules of the microorganisms producing gases and detecting the gas sources for applying bioenergy, a method for the orientation recognition of the gas source and its algorithm is presented in the paper. In the method, the dual-line gas …

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An acoustic gas concentration measurement algorithm for carbon monoxide in mixtures based on molecular multi-relaxation model

Ming Hua Zhu, Wang Shu, Donghai Xia

In this paper，we disclose the relations between multi-relaxation absorption and the acoustic parameters when ultrasound propagates in gas mixtures，such as the relation between concentrations of constituents and acoustic frequencies. In the meantime，the dependence of acoustic velocity on the same parameters is discussed. …

A Method Research on Orientation Estimation of Gas Signal Source Using Dual-Line Array

Donghai Xia, Shu Wang, Ming Zhu, Hui Nee Tang

For application researches of the detection for the gas signal source, a method for orientation estimation of the gas signal source in the two-dimensional space and its algorithm are presented in the paper. In the method, a mode of dual-line gas sensor …

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A method research on fire source localization using dual-line gas sensor array

Donghai Xia, Shu Wang, Ming Fang Zhu, Hui Tang

Fire source localization is an important direction in the research area of fire detection. For application researches of fire source localization in fire nonage, a method of fire source localization and its algorithm are presented in the paper, via. transforming the task …

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An algorithm for carbon monoxide concentration detection based on molecular multi-relaxation model

Ming Zhu, Shu Wang, Shutao Wang, Donghai Xia

In this paper, we focus on the relaxation process of acoustic waves in polyatomic gases, and build up a multi-relaxation algorithmic model of a gas mixture of nitrogen, oxygen, water vapor and carbon monoxide. The model is basing on the complicated transfer …

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Developed Acoustic Multi-relaxation Algorithm for Humidity Measurement in Gas Mixtures

Ming Zhu, Shu Wang, Shutao Wang, Donghai Xia

In this paper, we focus on the relaxation process of acoustic waves in polyatomic gases, and build up a multi-relaxation algorithmic model of a gas mixture of nitrogen, oxygen and water vapor. The algorithmic is basing on the complicated transfer mechanism of …

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An Algorithm of Feeble Gas Signal Recognition for Bioenergy Detection Using Wireless Sensor Network

Donghai Xia, Shu Wang, Ming Zhu, Hui Nee Tang

For realizing the rules of microorganisms living behavior and detecting the distribution of its bioenergy, the method research of recognizing feeble biology signal using wireless sensor network for signal detection is discussed in the paper. An algorithm of feeble signal recognition for …

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