Mônica Regina Hosannah da Silva e Silva

Accès ouvert 2026 article OpenAlex

Renal and endothelial biomarkers in Chagas disease in the Brazilian Amazon region: Early indicators of kidney injury and disease progression

Alba Regina Jorge Brandão, Jorge Augusto de Oliveira Guerra, Jessica Vanina Ortiz, Débora Raysa Teixeira de Sousa et autres

ABSTRACT Chagas disease (CD) is a significant public health problem in the Amazon, where the acute phase and oral transmission—often via contaminated açaí—are predominant. These peculiarities influence clinical severity and immunological responses, highlighting the need to investigate non-traditional biomarkers for early detection …

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0 citations PLoS ONE

Accès ouvert 2026 article OpenAlex

Evaluation of the autonomic nervous system in autochthonous patients from Amazon with acute Chagas disease treated with benznidazole

Mônica Regina Hosannah da Silva e Silva, Débora Raysa Teixeira de Sousa, Jessica Vanina Ortiz, Matheus Martins Monteiro et autres

Chagas disease, a neglected tropical disease, is endemic in the Amazon region, where oral transmission predominates. Autonomic nervous system (ANS) impairment is a recognized pathophysiological mechanism contributing to disease progression, including Chagas cardiomyopathy. This study aimed to assess ANS function in patients …

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1 citation PLoS neglected tropical diseases

Accès ouvert 2026 article OpenAlex

Overview of Chagas disease in Amazonas: an integrated approach

Maria das Graças Vale Barbosa Guerra, Flávio Renan Paula da Costa Alcântara, Alba Regina Jorge Brandão, Rômulo de Morais e Oliveira et autres

In the Amazon, Chagas disease (CD) transmission is associated with the consumption of contaminated foods -most notably açaí-and constitutes an important public health concern. In Brazil, the state of Amazonas ranks third in acute-phase notifications among states in the region, with 25% …

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0 citations Revista da Sociedade Brasileira de Medicina Tropical

Accès ouvert 2025 article OpenAlex

Autonomic dysfunction and Chagas Disease: what we know and what we need to integrate into clinical practice

Mônica Regina Hosannah da Silva e Silva, Débora Raysa Teixeira de Sousa, Jessica Vanina Ortiz, Elsa Isela Guevara-Moctezuma et autres

Objective: To provide a general, comprehensive and up-to-date overview of the action of the autonomic nervous system in Chagas' disease and the validation of Heart Rate Variability (HRV) as a tool for assessing the autonomic nervous system in Chagas' disease. Methods: This …

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0 citations Revista Eletrônica Acervo Saúde

2025 article OpenAlex

Evaluation of itraconazole monotherapy versus its combination with a single dose of pentamidine for treating cutaneous leishmaniasis caused by Leishmania (Viannia) guyanensis in Amazonas state, western Brazilian Amazon

Melissa de Sousa Melo Cavalcante, Laura Eduarda Miranda da Silva, Jessica Vanina Ortiz, Rômulo Freire de Morais et autres

BACKGROUND: Cutaneous leishmaniasis has long been a neglected tropical disease mainly due to therapy limitations. The search for safe and effective alternative treatments, particularly oral medications, has led to the development of second-line treatments, such as azole antifungals, including itraconazole. This study …

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3 citations Tropical Medicine & International Health

Accès ouvert 2025 article OpenAlex

The use of mesenchymal stem cells in the treatment of osteogenesis imperfecta: An integrative and qualitative review of literature

Kamily Iracema Coimbra Lima, Isac da Silva Monteiro, Kilder L Ribeiro, Mônica Regina Hosannah da Silva e Silva et autres

Osteogenesis Imperfecta (OI) is a hereditary bone disease that affects children, resulting in extreme bone weakness leading to musculoskeletal deformities and fractures. OI is caused by mutations in the genes that code to produce collagen in bones, a substance essential for the …

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0 citations Research Society and Development

Accès ouvert 2024 book-chapter OpenAlex