R.M. Dominic Meek

Learning from Charnley: implant retrieval in modern hand surgery

Jonathan R.A. Phillips, Keith Tucker, John Timperley, R.M. Dominic Meek

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2025 ICM: Two-Stage

Abhay Elhence, Christoph Böhler, Frank Kolhoff, Andrew Fraval et autres

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Synthetic peptide hydrogels as a model of the bone marrow niche demonstrate efficacy of a combined CRISPR-CAR T-cell therapy for acute myeloid leukaemia

W. Sebastian Doherty-Boyd, Penelope M. Tsimbouri, Vineetha Jayawarna, Matthew Walker et autres

Leukaemias, driven by mutations in haematopoietic stem cells (HSCs), rely on interactions with the bone marrow (BM) niche and other cell populations such as mesenchymal stromal cells (MSCs) for growth and survival. While chimeric antigen receptor (CAR) T-cell therapy shows promise for …

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Stakeholder prioritization preferences for individuals awaiting hip and knee arthroplasty

Luke Farrow, Diane L. Smith, R.M. Dominic Meek, Mandy Ryan et autres

Aims: Prolonged waits for hip and knee arthroplasty have raised questions about the equity of current approaches to waiting list prioritization for those awaiting surgery. We therefore set out to understand key stakeholder (patient and surgeon) preferences for the prioritization of patients …

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Latest developments in arthroplasty for hip fractures

John W. Kennedy, R.M. Dominic Meek

Hip fractures pose a major global health challenge, leading to high rates of morbidity and mortality, particularly among the elderly. With an ageing population, the incidence of these injuries is rising, exerting significant pressure on healthcare systems worldwide. Despite substantial research aimed …

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Association between surgeon and hospital volume and outcome of first-time revision hip arthroplasty for aseptic loosening

Richard James Holleyman, S Jameson, R.M. Dominic Meek, Vikas Khanduja et autres

Aims: This study evaluates the association between consultant and hospital volume and the risk of re-revision and 90-day mortality following first-time revision of primary hip arthroplasty for aseptic loosening. Methods: We conducted a cohort study of first-time, single-stage revision hip arthroplasties (RHAs) …

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Proceedings of the United Kingdom Periprosthetic Joint Infection Meeting 2022: Fracture-Related Infection Session

Nima Razii, Alex Hrycaiczuk, David William Shields, R.M. Dominic Meek et autres

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Does delay to theatre influence morbidity or mortality in femoral periprosthetic fractures?

John W. Kennedy, Elliot J. Rooney, P. J. Ryan, Soorya Siva et autres

Aims: Femoral periprosthetic fractures are rising in incidence. Their management is complex and carries a high associated mortality. Unlike native hip fractures, there are no guidelines advising on time to theatre in this group. We aim to determine whether delaying surgical intervention …

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Consultant revision hip arthroplasty volumes and new consultant volume trajectories in England, Wales, Northern Ireland, and the Isle of Man

Richard James Holleyman, Simon S Jameson, Mike R. Reed, R.M. Dominic Meek et autres

Aims: This study describes the variation in the annual volumes of revision hip arthroplasty (RHA) undertaken by consultant surgeons nationally, and the rate of accrual of RHA and corresponding primary hip arthroplasty (PHA) volume for new consultants entering practice. Methods: National Joint …

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Proceedings of the United Kingdom Periprosthetic Joint Infection Meeting 2022: Combined and Arthroplasty Sessions

Nima Razii, David William Shields, Alex Hrycaiczuk, Rhidian Morgan‐Jones et autres

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Is it time to reconsider the use of hydrogen peroxide in hip and knee arthroplasty?

Omer M. Farhan‐Alanie, John W. Kennedy, R.M. Dominic Meek, Fares Sami Haddad

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The association of dual-mobility total hip arthroplasty with dislocation compared to conventional hip arthroplasty for neck of femur fracture

Matthew C.A. Arnold, John W. Kennedy, Evan M. Wright, Madeleine Reece et autres

Introduction Neck of femur fractures are extremely common worldwide and have a mortality rate of 15% at 1 year. Dual-mobility cups (DMCs) have demonstrated a reduction in dislocation and revision rates for elective total hip arthroplasty (THA) but the benefits of DMC …

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