M. Hajime

Tofogliflozin long-term effects on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes mellitus lacking a history of cardiovascular disease: a 2-year extension study of the UTOPIA trial

Naoto Katakami, Tomoya Mita, Hidenori Yoshii, Toshihiko Shiraiwa et autres

BACKGROUND: This study aimed to assess the long-term effects of tofogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes lacking an apparent history of cardiovascular disease. METHODS: This was a prospective …

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The Influence of Tofogliflozin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus

Naoto Katakami, Tomoya Mita, Hidenori Yoshii, Toshihiko Shiraiwa et autres

INTRODUCTION: Treatment-related quality of life (QOL) is an important aspect of diabetes management. We evaluated the influence of a sodium-glucose cotransporter 2 (SGLT2) inhibitor, tofogliflozin, on treatment-related QOL in Japanese patients with type 2 diabetes mellitus (T2DM). METHODS: This is the prespecified …

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Burn-induced subepicardial injury in frog heart: a simple model mimicking ST segment changes in ischemic heart disease

Tatsuya Kikuchi, Itsuro Kazama, Mori Tomohiro, M. Hajime

Platelet-endothelial cell interaction in brain microvessels of angiotensin II type 1 receptor knockout mice following transient bilateral common carotid artery occlusion

Takuya Fukuoka, Hatta Takeshi, Hai Makiko, M. Hajime et autres

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