Francesco Giuseppe Martire

Adenomyosis, Infertility and Maternal–Fetal Outcomes: Diagnostic and Therapeutic Strategies Across Disease Phenotype—A Narrative Review

Francesco Giuseppe Martire, Eugenia Costantini, Ilaria Ianes, Claudia d’Abate et autres

Adenomyosis is a chronic estrogen-dependent disorder that may adversely affect reproductive health. Increasing evidence suggests that its reproductive and obstetric consequences may vary according to disease phenotype, including focal versus diffuse forms and inner versus outer myometrial localization. This narrative review summarizes …

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Profiling miRNA in salivary samples from subjects with endometriosis: a pilot study

Graziella Calugi, Francesca Blandino, Carla Proserpio, Luca Forlani et autres

Introduction: Endometriosis is a common, chronic, estrogen-dependent gynecological disorder characterized by the growth of endometrial-like tissue outside the uterus and frequently associated with pelvic pain and infertility. Despite its high prevalence, the molecular mechanisms underlying lesion persistence and inflammation remain poorly understood, …

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Transvaginal Sonographic Features of Diffuse Adenomyosis and Associated Symptoms in 18–30-Year-Old Nulligravid Women Without Endometriosis: Is Our Diagnosis Still Valid 10 Years Later? A Re-Evaluation of Previous Results

Irene Colombi, Francesco Giuseppe Martire, Eugenia Costantini, Ilaria Ianes et autres

Background: The introduction of the Morphological Uterus Sonographic Assessment (MUSA) 2022 criteria for diagnosing adenomyosis has reduced diagnoses compared with previous criteria. However, the impact of each ultrasonographic sign on diagnosis and symptom management remains unexplored. Methods: We retrospectively re-evaluated data from …

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SF1 miRNA Differential Expression and Sample Clustering Analysis in endometriosis

Lucia Buccarello, Graziella Calugi, Francesca Blandino, Carla Proserpio et autres

Endometriosis is a common, chronic, estrogen-dependent gynecological disorder characterized by the growth of endometrial-like tissue outside the uterus and frequently associated with pelvic pain and infertility. Despite its high prevalence, the molecular mechanisms underlying lesion persistence and inflammation remain poorly understood, limiting …

SF1 miRNA Differential Expression and Sample Clustering Analysis in endometriosis

Lucia Buccarello, Graziella Calugi, Francesca Blandino, Carla Proserpio et autres

Endometriosis is a common, chronic, estrogen-dependent gynecological disorder characterized by the growth of endometrial-like tissue outside the uterus and frequently associated with pelvic pain and infertility. Despite its high prevalence, the molecular mechanisms underlying lesion persistence and inflammation remain poorly understood, limiting …

Ultrasound-guided radiofrequency ablation of an intramural fibroid in a woman desiring fertility with coexisting focal adenomyosis: a case report

Francesco Giuseppe Martire, Claudia d’Abate, Eugenia Costantini, Ilaria Ianes et autres

Objective: To report the reproductive outcome after ultrasound-guided radiofrequency ablation (RFA) in a woman with an intramural uterine fibroid and coexisting focal adenomyosis who experienced infertility and desired pregnancy. Design: Case report. Patient: A 40-year-old nulligravid woman with heavy menstrual bleeding, dysmenorrhea, …

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Abdominal Wall Elevation for Pneumoperitoneum in Laparoscopic Gynecologic Surgery: A Retrospective Comparative Study of Experienced and Trainee Surgeons

Francesco Giuseppe Martire, Ilaria Ianes, Eugenia Costantini, Errico Zupi et autres

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Role of Lifestyle and Nutrition in Menstrual Cycle Regularity: Associations with Body Composition and Dietary Habits

A. Andréoli, Eugenia Costantini, Qeta Megan, Artida Pashaj et autres

Background: Nutritional status and lifestyle factors are increasingly recognized as relevant modulators of women’s reproductive health. However, data remain limited on the relationship between body composition, dietary habits, and menstrual cycle characteristics in apparently healthy young women. This study aimed to assess …

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Premenstrual Syndrome and Nutritional Factors: A Narrative Review of Current Evidence and Clinical Implications

Francesco Giuseppe Martire, Eugenia Costantini, Ilaria Ianes, Claudia d’Abate et autres

Premenstrual syndrome is a common hormone-related condition marked by recurrent physical and affective symptoms that can substantially impair daily functioning. While cyclical ovarian hormone fluctuations are physiological, clinically relevant symptoms occur only in a subset of women, indicating the contribution of individual …

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Ectopic Pregnancy with a Normally Located Levonorgestrel-Releasing Intrauterine System in a Woman with Adenomyosis: Case Report and Literature Review

Francesco Giuseppe Martire, Eugenia Costantini, Errico Zupi, L Lazzeri

Background: Ectopic pregnancy (EP) is a potentially life-threatening condition, often associated with acute abdominal pain and hemoperitoneum. Certain conditions, such as adenomyosis and the use of long-acting reversible contraceptives (LARC), may represent risk factors for the development of ectopic pregnancy. Management is …

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Correlation between ultrasonographic findings and histopathological and molecular characteristics in endometrial cancer: A multicenter study

Irene Colombi, Giuseppe Vizzielli, Silvia Pisaneschi, Federica Perelli et autres

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Sonographic and Clinical Progression of Adenomyosis and Coexisting Endometriosis: Long-Term Insights and Management Perspectives

Francesco Giuseppe Martire, Claudia d’Abate, Maria De Bonis, Giuseppe Sorrenti et autres

Objectives: To evaluate the impact of hormonal therapy on the evolution of painful symptoms in premenopausal women with adenomyosis, with or without concomitant endometriosis, over an 18-month follow-up period. This study aimed to compare the symptomatic progression between treated and untreated patients, …

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