Impact of HPLC Parameters on Chiral Separation of Nornicotine Enantiomers
M. Ashraf-Khorassani, William M. Coleman, Weston M. Umstead
Summary Given the well-documented pharmacological differences between nicotine and nornicotine enantiomers, understanding their distribution is essential. This knowledge also helps authenticate the enantiomers’ source (natural or synthetic). To improve the quantitative determination methods for these distributions, the influence of additives, modifiers, and …
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