Accès ouvert
2026
article
OpenAlex
Meng Shu, Wenjie Cheng, Fangyang Yu, Liyin Zhang et autres
Atherosclerosis (AS)-associated cardiovascular disease is the main cause of global mortality. The excessive retention of glycated low-density lipoprotein (G-LDL) under the vascular endothelium promotes AS. In addition, G-LDL supports a role in promoting the expression of scavenger receptor A (SR-A), increasing SR-A-mediated …
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Accès ouvert
2025
article
OpenAlex
Li Wang, Yi Song, Yan Shu, Baorui Xue et autres
OBJECTIVE: Caveolae are closely linked to the onset and progression of atherosclerosis. The pivotal involvement of caveolin-1 (CAV1) within the caveolae in atherosclerosis development has been consistently supported. However, the potential contributions of additional caveolae proteins to atherosclerosis necessitate further exploration. Therefore, …
cn
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Accès ouvert
2024
article
OpenAlex
Shiqin Fan, Baorui Xue, Jing Ma
To explore the causal relationship between gut microbiota (GM) and Idiopathic pulmonary fibrosis (IPF), we performed a two-sample Mendelian randomization (MR). GM was used as an exposure factor, and instrumental variables were determined from the GWAS of 18,340 participants. GWAS of IPF …
cn
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Accès ouvert
2024
article
OpenAlex
Liyin Zhang, Baorui Xue, Fangyang Yu, Yin Yao et autres
Background: Controversy persists regarding the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on cancer.The underlying causal relationship remains unclear.Method: A two-sample Mendelian randomization (MR) strategy was employed to investigate the causal associations between SGLT2 inhibitors and 26 site-specific malignancies.Instrumental variants strongly associated …
cn
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Accès ouvert
2023
article
OpenAlex
Yi Song, Ying Zhao, Yan Shu, Liyin Zhang et autres
Background Neutrophil/high-density lipoprotein (HDL) ratio (NHR), monocyte/HDL ratio (MHR), lymphocyte/HDL ratio (LHR), platelet/HDL ratio (PHR), systemic immune-inflammation index (SII), system inflammation response index (SIRI), and aggregate index of systemic inflammation (AISI) have been recently investigated as novel inflammatory markers. Herein, the correlation …
cn
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