Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers
Yani Zhao, Aspen T. Hawkins, Caroline A. Foley, Stephen V. Frye et autres
0 citationsUNC Libraries
Lindsey I. James
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146Publications signalées
3174Citations signalées
4Affiliations récentes
Institutions déclarées
Domaines associés
Epigenetics and DNA MethylationProtein Degradation and InhibitorsGenomics and Chromatin DynamicsCancer-related gene regulationUbiquitin and proteasome pathways
Publications récentes
Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl-lysine reader protein MPP8.
P Brian Hardy, Lindsey I. James, Juanita L Sanchez Rubiano, Peter H. Buttery et autres
0 citationsCarolina Digital Repository (University of North Carolina at Chapel Hill)
A screen of chromatin-targeting compounds identifies TAF1 as a novel regulator of HIV latency
Samuel D. Burgos, Airlie Ward, Manickam Ashokkumar, Kimberly Enders et autres
0 citationsmBio
Discovery of Small-Molecule Antagonists of PHF1 and 19 Demonstrates the Ligandability of PRC2 Accessory Proteins.
Lindsey I. James, Stephen V. Frye, Jiuyang Liu, Cathy J. Spangler et autres
0 citationsCarolina Digital Repository (University of North Carolina at Chapel Hill)
Structural basis of NSD2 degradation via targeted recruitment of SCF-FBXO22
Kevin Robertson, Sascha Josef Amann, Xianxi Wang, Irina Grishkovskaya et autres
1 citationNature Communications
Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression
Chengheng Liao, Siying Lyu, Rebecca L. Johnson, Tiantian Shang et autres
2 citationsCell chemical biology
Abstract B027: UNC8209: A potent and selective TBK1 degrader for ccRCC
Chengheng Liao, Siying Lyu, Rebecca L. Johnson, Xiaoyu Wang et autres
0 citationsCancer Research
Discovery of Small-Molecule Antagonists of PHF1 and 19 Demonstrates the Ligandability of PRC2 Accessory Proteins
Isabelle Amick, Rebecca L. Johnson, Jiuyang Liu, Cameron R. Bussey-Sutton et autres
0 citationsACS Bio & Med Chem Au
Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl-lysine reader protein MPP8
Juanita L. Sanchez Rubiano, Peter H. Buttery, Zachary A. Gurard‐Levin, Jacqueline L. Norris‐Drouin et autres
0 citationsSLAS DISCOVERY
Discovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer
Lindsey I. James, Stephen V. Frye, C.H. Arrowsmith, Amanda L. Graboski et autres
0 citationsCarolina Digital Repository (University of North Carolina at Chapel Hill)
Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7
Gang Greg Wang, Hagar F. Moussa, Dmitri Kireev, Jacqueline L. Norris et autres
0 citationsCarolina Digital Repository (University of North Carolina at Chapel Hill)
Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers
Chien-Chu Lin, Yani Zhao, Caroline A. Foley, Lindsey I. James et autres
5 citationsMolecular Cell
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