Monicah Nyambura

Factors associated with psychological distress in mothers and girls in Kenya: A baseline analysis

Monicah Nyambura, Catherine Kathure Kaimenyi, Dennis Kariuki Muriithi, Thomas Gordon et autres

BACKGROUND: Psychological distress may be an indicator of mental health, can lead to reduced life functioning, and is not well studied in African countries. OBJECTIVE: The aim of this analysis was to quantify psychological distress using the Kessler-6 (K-6) scale, which is …

Enabling Adherence to Treatment (EAT): a pilot study of a combination intervention to improve HIV treatment outcomes among street-connected individuals in western Kenya

Mia Kibel, Monicah Nyambura, Lonnie Embleton, Reuben Kiptui et autres

BACKGROUND: Street-connected individuals (SCI) in Kenya experience barriers to accessing HIV care. This pilot study provides proof-of-concept for Enabling Adherence to Treatment (EAT), a combination intervention providing modified directly observed therapy (mDOT), daily meals, and peer navigation services to SCI living with …

ca, Kenya, us (code pays fourni par la source)

Population-Based Estimates and Predictors of Child and Adolescent Linkage to HIV Care or Death in Western Kenya

Stephanie M. DeLong, Yizhen Xu, Becky Lynn Genberg, Monicah Nyambura et autres

BACKGROUND: Population-level estimates of linkage to HIV care among children and adolescents (CAs) can facilitate progress toward 95-95-95 goals. SETTING: This study was conducted in Bunyala, Chulaimbo, and Teso North subcounties, Western Kenya. METHODS: Linkage to care was defined among CAs diagnosed …

us, Kenya, ca (code pays fourni par la source)

Tree-based subgroup discovery using electronic health record data: heterogeneity of treatment effects for DTG-containing therapies

Jiabei Yang, Ann Wairimu Mwangi, Rami Kantor, Issa J Dahabreh et autres

The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment effects using EHR data poses several challenges, including time-varying confounding, repeated and temporally non-aligned measurements of covariates, treatment assignments …

us, Kenya (code pays fourni par la source)

Implementation outcomes and strategies for delivering evidence-based hypertension interventions in lower-middle-income countries: Evidence from a multi-country consortium for hypertension control

Joyce Gyamfi, Juliet I Iwelunmor, Shivani Anil Patel, Vilma Edith Irazola et autres

Guidance on contextually tailored implementation strategies for the prevention, treatment, and control of hypertension is limited in lower-middle income countries (Lower-MIC). To address this limitation, we compiled implementation strategies and accompanying outcomes of evidence-based hypertension interventions currently being implemented in five Lower-MIC. …

us, ar, vn, Kenya, Ghana, gt, in (code pays fourni par la source)

Tree-based Subgroup Discovery In Electronic Health Records: Heterogeneity of Treatment Effects for DTG-containing Therapies

Jiabei Yang, Ann Wairimu Mwangi, Rami Kantor, Issa J Dahabreh et autres

The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment effects using EHR data poses several challenges, including time-varying confounding, repeated and temporally non-aligned measurements of covariates, treatment assignments …

Development, Assessment, and Outcomes of a Community-Based Model of Antiretroviral Care in Western Kenya Through a Cluster-Randomized Control Trial

Suzanne M. Goodrich, Abraham Mosigisi Siika, Ann Wairimu Mwangi, Monicah Nyambura et autres

OBJECTIVE: To develop and assess an alternative care model using community-based groups for people living with HIV and facilitate by lay personnel. METHODS: Geographic locations in the Academic Model Providing Access to Healthcare Kitale clinic catchment were randomized to standard of care …

us, Kenya (code pays fourni par la source)

Population-based estimates of engagement in HIV care and mortality using double-sampling methods following home-based counseling and testing in western Kenya

Becky Lynn Genberg, Joseph W. Hogan, Yizhen Xu, Monicah Nyambura et autres

INTRODUCTION: Data on engagement in HIV care from population-based samples in sub-Saharan Africa are limited. The objective of this study was to use double-sampling methods to estimate linkage to HIV care, ART initiation, and mortality among all adults diagnosed with HIV by …

us, Kenya, ca (code pays fourni par la source)

The Confluence of Pregnancy and New Diagnosis of HIV Among Adolescent Women in Western Kenya

Katherine R. MacDonald, Edith Apondi, Mary A. Ott, Juddy Wachira et autres

us, np, Kenya, ca (code pays fourni par la source)

Evaluating strategies to improve HIV care outcomes in Kenya: a modelling study

Jack Olney, Paula K. A. Braitstein, Jeffrey W. Eaton, Edwin Sang et autres

BACKGROUND: With expanded access to antiretroviral therapy (ART) in sub-Saharan Africa, HIV mortality has decreased, yet life-years are still lost to AIDS. Strengthening of treatment programmes is a priority. We examined the state of an HIV care programme in Kenya and assessed …

gb, Kenya, ca, us (code pays fourni par la source)

Implementation and Operational Research

Beth Rachlis, Daniel Ochieng, Elvin Hsing Geng, Elyne Rotich et autres

BACKGROUND: Academic Model Providing Access To Healthcare (AMPATH) program provides comprehensive HIV care and treatment services. Approximately, 30% of patients have become lost to follow-up (LTFU). We sought to actively trace and identify outcomes for a sample of these patients. METHODS: LTFU …

Kenya, ca, us, jp (code pays fourni par la source)

Linkage to and engagement in HIV care in western Kenya: an observational study using population-based estimates from home-based counselling and testing

Becky Lynn Genberg, Violet Naanyu, Juddy Wachira, Joseph W. Hogan et autres

us, Kenya (code pays fourni par la source)