Sanyog G. Shitole

Associations Between Sustained Methamphetamine/Amphetamine Use and Left Ventricular Dysfunction in a Cohort of Women Living With and Without HIV.

Jorge R. Kizer, Michelle Floris-Moore, Claudia Martinez, Denise Christina Vidot et autres

Substance use is associated with cardiac disease, and women with HIV have a disproportionately high prevalence of substance use. However, the extent to which ongoing use of multiple substances relates to specific cardiovascular conditions in women with HIV and sociodemographically similar women …

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Brief Report: Association of HIV and HCV With Adverse Coronary Artery Phenotypes in Women: Findings From a Cross-Sectional Study

Sanyog G. Shitole, Ethan Chen, Mahim Naveed, X. Xue et autres

BACKGROUND: HIV and hepatitis C virus (HCV) have each been associated with increased risk of coronary heart disease events. Coronary computed tomography angiography (CCTA) has linked HIV to noncalcified plaque, and HCV to both calcified and noncalcified plaque, but available data come …

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Associations Between Sustained Methamphetamine/Amphetamine Use and Left Ventricular Dysfunction in a Cohort of Women Living With and Without HIV

Elise D. Riley, Yifei Ma, Kathérine C. Wu, Sanyog G. Shitole et autres

BACKGROUND: Substance use is associated with cardiac disease, and women with HIV have a disproportionately high prevalence of substance use. However, the extent to which ongoing use of multiple substances relates to specific cardiovascular conditions in women with HIV and sociodemographically similar …

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Abstract 4366949: Relations Of Inflammatory Biomarkers With Incident Clinical Peripheral Artery Disease In Older Adults

Jagjot Dosanjh, Parveen K. Garg, Kenneth Jay Mukamal, Mary Cushman et autres

Background: Peripheral artery disease (PAD) is a vascular condition marked by arterial narrowing that affects 8.5 million adults in the U.S. Contributions of circulating biomarkers reflecting different immune pathways have not been well established in large population-based studies of older adults. Research …

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Adverse childhood experiences, sexual orientation-related victimization, and cardiovascular disease risk among men with and without HIV

Allison A. Appleton, Serim Lee, Mark H. Kuniholm, Elizabeth Vásquez et autres

OBJECTIVE: Adverse childhood experiences (ACEs) are traumatic events occurring before age 18 and can increase cardiovascular disease (CVD) risk. Many sexual minority men (SMM) and men with HIV (MWH) have trauma histories and elevated CVD risk. We investigated the association between ACEs …

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MACHINE LEARNING PREDICTS ONE YEAR MORTALITY BUT NOT READMISSION AFTER ST ELEVATION MYOCARDIAL INFARCTION

Muhammad Umer Farooq, Hiten Doshi, Miguel Alvarez Villela, Rohan A. Kankaria et autres

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Non-Esterified Fatty Acid Profiles and Cause-Specific Mortality: The Cardiovascular Health Study

Yakubu Bene‐Alhasan, Sanyog G. Shitole, Petra Bůžková, Calvin H. Hirsch et autres

CONTEXT: Total fasting non-esterified fatty acid (NEFA) levels have been associated with mortality. The corresponding associations with NEFA levels following an oral glucose tolerance test (OGTT) and with individual fasting NEFA species are unclear. OBJECTIVE: We evaluated the associations of post-load NEFA, …

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Abstract P1160: Gut Microbiota, Circulating Inflammatory Markers, and Cardiac Dysfunction In Women Living With HIV

Zheng Wang, Sanyog G. Shitole, Anjali Sharma, David B. Hanna et autres

Introduction: The relationships among gut microbial alterations, host inflammation, and cardiac dysfunction remain understudied, particularly in the context of HIV. Hypothesis: We hypothesized that higher abundance of pro-inflammatory gut bacteria is associated with higher levels of host circulating inflammatory makers and cardiac …

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Assessment of Inflammatory Biomarkers and Incident Atrial Fibrillation in Older Adults

Sanyog G. Shitole, Susan R. Heckbert, Gregory M. Marcus, Sanjiv Jayendra Shah et autres

BACKGROUND: Available evidence supports the importance of inflammation in atrial fibrillation (AF) pathogenesis, yet general anti-inflammatory therapies have failed to show benefit for prevention of the arrhythmia. Better understanding of the specific inflammatory pathways involved is necessary to advance therapeutics. METHODS AND …

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Abstract P175: Total Fasting and Post-Load and Individual Fasting Non-Esterified Fatty Acids and Total and Cause-Specific Mortality: The Cardiovascular Health Study

Yakubu Bene‐Alhasan, Sanyog G. Shitole, Nirupa Rachel Matthan, Alice Hinda Lichtenstein et autres

Background: Total fasting non-esterified fatty acid (NEFA) levels have been associated with total and cause-specific mortality in older adults, but the corresponding associations with NEFA levels following the metabolic challenge of an oral glucose tolerance test (OGTT) and with individual fasting NEFA …

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HIV, HIV-Specific Factors, and Myocardial Disease in Women

Yoko Kato, Bharath Ambale‐Venkatesh, Mahim Naveed, Sanyog G. Shitole et autres

BACKGROUND: People with human immunodeficiency virus (HIV) (PWH) have an increased risk of cardiovascular disease (CVD). Cardiac magnetic resonance (CMR) has documented higher myocardial fibrosis, inflammation, and steatosis in PWH, but studies have mostly relied on healthy volunteers as comparators and focused …

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Human Immunodeficiency Virus and Cardiac End-Organ Damage in Women: Findings From an Echocardiographic Study Across the United States

A.A. Adimora, Ighovwerha Ofotokun, D.J. Konkle-Parker, Cynthia C. Taub et autres

BACKGROUND: People with human immunodeficiency virus (HIV) have been reported to have increased risk of clinical and subclinical cardiovascular disease. Existing studies have focused on men and often have been uncontrolled or lacked adequate HIV-negative comparators. METHODS: We performed echocardiography in the …

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