Calvin Guan

The Montreal Cognitive Assessment at the Framingham Heart Study: A Re‐Examination of the Norms

Emma Muller, Calvin Guan, Katherine A. Gifford, Preeti Sunderaraman et autres

OBJECTIVES: There is a lack of consensus regarding what constitutes cognitively normal performance on the Montreal Cognitive Assessment (MoCA) based on demographic characteristics. Further, research regarding normative data on the MoCA for middle-aged individuals is relatively limited. The current study sought to …

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Psychometric modeling of Boston process approach data for dementia prediction in the Framingham Heart Study

Brandon Frank, Ashita S. Gurnani, Landon Hurley, Calvin Guan et autres

OBJECTIVES: Neuropsychological (NP) tests are multi-domain in execution. Reliance on a single score representing specific domains obscures the detection of subtle cognitive changes and increases risk of inaccurate assessment. Rooted in the Boston Process Approach (BPA), the Framingham Heart Study (FHS) captures …

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Author response for "The Montreal Cognitive Assessment at the Framingham Heart Study: A re- examination of the norms"

Emma Muller, Calvin Guan, Katherine A. Gifford, Preeti Sunderaraman et autres

A functional perspective on the conditional covariance comparison problem in dementia analysis

Calvin Guan, Ashis Gangopadhyay

Although there are many methods available in the literature to compare the covariance structures of two populations, few are suitable for clinical application due to the inability to account for covariate(s) that affect the dependence structure of the variables being investigated. A …

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A - 3 Quantifying the Richness of the Boston Process Approach (BPA) Using a Novel Analytic Approach: the Framingham Heart Study

Ashita S. Gurnani, Brandon Frank, Calvin Guan, Stacy L. Andersen et autres

Abstract Objective Neuropsychological (NP) tests are often interpreted with a one test-one domain analytic approach in research, which misrepresents their clinical utility. The Boston Process Approach (BPA) allows for extraction of multi domain features within and across NP tests although its use …

Analyzing the covariance structure of plasma signaling proteins in relation to the diagnosis of dementia

Calvin Guan, Rhoda Au, Ting Fang Alvin Ang, Ashis Gangopadhyay

Abstract Numerous studies have shown that individuals with dementia have exhibited activation of inflammatory pathways in their brains. Typically, these studies use traditional and well-established regression methods for data analysis. In this paper, a new approach is introduced that utilizes the analysis …

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