JANNETTE B. PAPPAS

Hemodynamic effects of N-acetylamrinone in a porcine model of group B streptococcal sepsis.

Elizabeth M. Allen, Mark E. Rowin, JANNETTE B. PAPPAS, D D Vernon et autres

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HPLC micromethod for amrinone and metabolites in patients receiving concurrent cephalosporin therapy

JANNETTE B. PAPPAS, Elizabeth M. Allen, Mitchell P. Ross, William Banner

Amrinone (AMR), a bipyridine derivative, is receiving increasing use in postoperative cardiac patients as an inotrope and vasodilator. The hemodynamic response to amrinone in adults is linearly related to AMR concentrations, warranting therapeutic drug monitoring. We report a rapid microsample HPLC method …

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Oral Dimercaptosuccinic Acid and Ongoing Exposure to Lead: Effects on Heme Synthesis and Lead Distribution in a Rat Model

JANNETTE B. PAPPAS, J. Thomas Ahlquist, Elizabeth M. Allen, William Banner

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A PHARMACOKINETIC STUDY COMPARING INTERMITTENT VS CONTINUOUS INFUSION KETOROLAC IN A PEDIATRIC INTENSIVE CARE UNIT (PICU)

Keith A. Kerr, William Banner, JANNETTE B. PAPPAS, J. Thomas Ahlquist

The Lead Debate Goes On

William Banner, Barbara Insley Vuignier, JANNETTE B. PAPPAS

In Reply.— I am glad that Dr Marcus has pinched himself and woken up to 1993 hope he will now review some of the literature that he alludes to in his letter. Although I also believe that the intentions of the CDC …

Amrinone-associated thrombocytopenia: Pharmacokinetic analysis

Mitchell P. Ross, ELIZABETH M. ALLEN-WEBB, JANNETTE B. PAPPAS, Edwin C. McGough

Amrinone-associated thrombocytopenia is thought to result from nonimmune-mediated peripheral platelet destruction. Platelet destruction may be a concentration-dependent toxic effect of amrinone or its principal metabolite N-acetylamrinone. Eighteen children receiving amrinone after heart surgery were prospectively evaluated to correlate the pharmacokinetics of amrinone …

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Mythology of Lead Poisoning

William Banner, Barbara Insley Vuignier, JANNETTE B. PAPPAS

To the Editor.— The commentary offered by Needleman and Jackson1 has raised some interesting points for discussion regarding the mythology surrounding the issue of lead poisoning and its treatment. Whereas the opening statement of the authors suggests that standards of practice are …