Xiaoyi Yang

CD27 agonism enhances long-lived CD4 T cell vaccine responses critical for antitumor immunity

Bin-Jin Hwang, Erika J. Crosby, David T. Severson, Timothy N. Trotter et autres

Tumor antigen vaccination represents an appealing approach for cancer but has failed to materialize as oncologic standard of care. To understand long-term vaccine efficacy, we conducted a retrospective analysis of patients with human epidermal growth receptor 2 + (HER2 + ) breast …

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Towards the strategies of return to sport after lateral ankle Sprain: a systematic review

Hanhui Jiang, Qichang Mei, Yuan Wang, Xiaoyi Yang et autres

BACKGROUND: Returning to sport (RTS) from lateral ankle sprain (LAS) is multifaceted and interdisciplinary. This systematic review aimed to investigate the factors involved in RTS and further establish a standard paradigm of RTS to treat and rehabilitate the LAS. METHODS: Four electronic …

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Statistical shape analysis of marathon foot

Qichang Mei, Yuming Wang, Xiaoyi Yang, Fengqin Fu et autres

Statistical Shape Modelling (SSM) has been a popular tool to explain the shape variability in a cohort of objects in certain populations (Mei et al., 2021a, 2021b). As the key step, principal compo...

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Chasse-Step and One-Step Footwork Reported Different Biomechanical Profiles in Elite Table Tennis Athletes

Xiaoyi Yang, Yuming Wang, Qichang Mei, Shirui Shao et autres

Table tennis athletes are required to execute appropriate footwork moving to the best position to hit the ball, while the chasse-step and one-step are typically employed in table tennis. This study aims to examine the difference in joint angles, joint moments, joint …

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Global landscape of mesenchymal stem-cell clinical trials for osteoarthritis: a comprehensive registry analysis and policy implications

Yijie Gao, Peng Lin, Xiaoyi Yang, Rong Xu et autres

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Abstract 2128: Uncovering the multiple therapeutic mechanisms of trastuzumab deruxtecan (T-DXd): effective extracellular payload release and immunomodulatory stimulation

Li-Chung Tsao, John S. Wang, Xingru Ma, Joey V. Ragusa et autres

Trastuzumab deruxtecan (T-DXd), also known as fam-trastuzumab-deruxtecan-nxki, is a novel HER2-targeting antibody-drug conjugate (ADC) that has shown remarkable clinical efficacy in breast cancer (BC) and other cancers with varying levels of HER2 expression. However, the mechanisms underlying its activity in HER2-low and …

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Understanding the biomechanical influence of core contribution in squat: A systematic review

Xiaoyi Yang, Yile Wang, Justin Fernandez, Qichang Mei et autres

Background Squat exercises have been widely employed in fitness, rehabilitation, sports performance, and strength training under either free weight or weight-bearing conditions. Objectives To report the evidence regarding the core contribution of biomechanical changes in the trunk and lower limbs of physical …

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A disproportionality analysis of adverse events associated with loop diuretics in the FDA Adverse Event Reporting System (FAERS)

Xi Liu, Qifeng Liu, Xiaoyi Yang, Lixia Yu

BACKGROUND: Loop diuretics, including furosemide, torsemide, and bumetanide, are widely utilized in the management of volume overload-related conditions. Although previous studies have extensively documented risks such as electrolyte imbalances, ototoxicity, and nephrotoxicity, real-world evidence regarding novel or underrecognized adverse event (AE) signals …

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Research of the lattice wave properties of two-dimensional dusty plasma

Rui-Jin Cheng, Z Liu, Kehu Yang, Xiaoyi Yang

As a complex system with many complex physical processes, dust plasma provides a medium for the study of nonlinear and non-equilibrium physics. Especially because it is macroscopic visible and isomorphic with microscopic process physics, it provides a macroscopic reference for the study …

BDEL: A Backdoor Attack Defense Method Based on Ensemble Learning

Zhihuan Xing, Yuqing Lan, Yin Yu, Yong Cao et autres

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Naked Gene Delivery Induces Autophagy for Effective Treatment of Acute Lung Injury in a Mouse Model

Hui Yu, Xiaoyi Yang, Songpei Li, Ao Shen et autres

Background: Acute lung injury (ALI) leads to diffuse pulmonary interstitial and alveolar edema, further developing into acute respiratory distress syndrome (ARDS). The present therapeutic approaches showed limited effects with poor clinical efficacy or severe side effects. This study aims to develop novel …

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Applied Research on Internet of Things Technology Enabling Intelligent Logistics

Xiaoyi Yang

The breakthrough progress of the Internet of Things (IoT) technology provides a new impetus for the digital transformation of intelligent logistics. This paper analyzes the current status of the application of IoT in the field of intelligent logistics, discusses its specific application …

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