Anthony Provenzano

Systemic Therapy for Melanoma: ASCO Guideline Update Q and A

Vernon K. Sondak, Michael B. Atkins, Hans Messersmith, Anthony Provenzano et autres

This Q&A answers questions regarding ASCO's recent Systemic Therapy for Melanoma guideline.

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Primary Atypical Hemolytic Uremic Syndrome Presenting with Raynaud Phenomenon Triggered by COVID-19

Husam El Sharu, Akil S. Kavcar, Tiffany Lee, Richard K. Grey et autres

Introduction: COVID-19 has been linked to atypical hemolytic uremic syndrome (aHUS), although skin manifestations are rarely reported. Case Description: A 48-year-old female with Mixed connective tissue disease (MCTD) presented after COVID-19 with Raynaud's phenomenon. Blood film showed schistocytes, ADAMTS13 level was 45%, …

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Hypereosinophilic syndrome with leptomeningeal involvement: a not-so-classical case report of classical Hodgkin Lymphoma

George Mellgard, Elina Stoffel, Alissa Michel, Fatima Iqbal et autres

Hypereosinophilic syndrome (HES)is a rare disorder affecting only 0.36 in 100,000 estimated individuals a year [1]. Typically, hypereosinophilia is divided into primary or neoplastic, secondary or ...

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Systemic Therapy for Melanoma: ASCO Guideline Update

Rahul Seth, Sanjiv S. Agarwala, Hans Messersmith, Krishna Alluri et autres

PURPOSE To provide guidance to clinicians regarding the use of systemic therapy for melanoma. METHODS American Society of Clinical Oncology convened an Expert Panel and conducted an updated systematic review of the literature. RESULTS The updated review identified 21 additional randomized trials. …

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Systemic Therapy for Melanoma: ASCO Guideline

Rahul Seth, Hans Messersmith, Varinder Kaur, John M. Kirkwood et autres

PURPOSE To provide guidance to clinicians regarding the use of systemic therapy for melanoma. METHODS ASCO convened an Expert Panel and conducted a systematic review of the literature. RESULTS A systematic review, one meta-analysis, and 34 additional randomized trials were identified. The …

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Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update

Arlene A. Forastiere, Nofisat Ismaila, Jan S. Lewin, Cherie‐Ann O. Nathan et autres

Purpose To update the guideline recommendations on the use of larynx-preservation strategies in the treatment of laryngeal cancer. Methods An Expert Panel updated the systematic review of the literature for the period from January 2005 to May 2017. Results The panel confirmed …

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Evaluating Chemotherapy at the End of Life

Anthony Provenzano, Richard D. Carvajal

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A Paleontology Primer for Oncologists

Anthony Provenzano

Just as a blazing meteor wiped out large dinosaurs, health care reform may eliminate solo practitioners.

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Simone's OncOpinion on Clinical Trials (12/25/08)

Anthony Provenzano

The “Clinical Trials in Trouble” column underscores how the inertia that is inherent in the system blunts the wide-eyed curiosity that drove us into medicine in the first place. Dr. Simone correctly points out that conflating Phase I and Phase II trials …

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