Antoine Khalil

Poster Session II – Poster of Distinction II A319 BIOACTIVE PHOSPHOLIPIDS AS MEDIATORS OF ALTERED BEHAVIOUR AND VISCERAL HYPERSENSITIVITY ASSOCIATED WITH MICROBIOTA FROM PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD)

F A Vicentini, J Pujo, Mikayla Hall-Bruce, G Rueda et autres

Abstract Background IBD affects globally over 6 million patients, who often suffer from chronic abdominal pain and psychiatric comorbidities that can persist in the absence of colitis. The gut microbiota is linked to IBD, pain and mood disorders, but its role in …

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CT features of interstitial lung disease in systemic lupus erythematosus and overlap lupus-other connective tissue disease

Aurore Sajust de Bergues de Escalup, Arthur Mageau, Lou Deneuville, Karim Sacré et autres

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Durvalumab in Patients With Treatment-Naive Stage IV NSCLC With an ECOG Performance Status of 2 to 3 and High PD-L1 Tumor Expression (IFCT-1802 SAVIMMUNE): A Multicenter Phase 2 Trial

V. Gounant, Laurent Greillier, Céline Mascaux, F. Pinquié et autres

Introduction: Eastern Cooperative Oncology Group performance status 2 to 3 is associated with poor survival and chemotherapy-related adverse events (AEs). The impact of poor PS on the safety and efficacy of immune checkpoint inhibitors has not been elucidated. This study aimed to …

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MUC5B polymorphism and post COVID-19 lung abnormalities on chest CT-scan

Celestie Yaacoub, Coralie Tardivon, Jean G. Dib, Spyridon Prountzos et autres

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Mise en œuvre d’une réunion de concertation pluridisciplinaire dédiée à la radiothérapie interne vectorisée par ligands du PSMA couplés au 177Lu

L. Turpin, Antoine Khalil, Françoise Montravers, Sarah Boughdad et autres

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A23 INVESTIGATING THE LINK OF BACTERIAL TRANSLOCATION AND BEHAVIORAL CHANGES IN A MOUSE RESTRAINT STRESS MODEL

Chiko Shimbori, Antoine Khalil, Narjis Kraïmi, Jun Lü et autres

Abstract Background Bacterial translocation is defined as migration of bacteria or bacterial fragments from the intestinal lumen into extraintestinal tissues; this process has been implicated in the pathophysiology of gastrointestinal disorders and central nervous system disorders. However, the direct causal relationship between …

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Neuroimaging for prognosis of central nervous system infections: a systematic review and meta-analysis

Augustin Gaudemer, Netanel Covier, Marie-Cécile Henry–Feugeas, Jean‐François Timsit et autres

BACKGROUND: Central nervous system (CNS) infections carry a severe prognosis and often require intensive care unit (ICU) admission. This study evaluated the prognostic value of neuroimaging in patients with all-type CNS infections. METHODS: Using a predefined strategy, we first conducted a systematic …

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Brain microstructural damage through serial diffusion tensor imaging and outcomes in Susac syndrome: A prospective cohort study

Augustin Gaudemer, Marie-Cécile Henry–Feugeas, Marion Peyre, Alexandra Kachaner et autres

BACKGROUND: Susac syndrome (SuS) is a rare immune-mediated microangiopathy with potential disabling evolution. We aimed to analyze brain microstructural damage through diffusion tensor imaging (DTI) in SuS and determine its association with poor outcomes. METHOD: CarESS study is a prospective multicenter national …

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Prognosis of incidental lung cancer in lung transplant candidates

Clémentine Bouchez, Chahine Medraoui, Aurélie Cazes, Antoine Khalil et autres

BACKGROUND: Incidental lung cancer, in the field of lung transplantation (LTx), is more often related to malignancies diagnosed in explants or transplanted organs. Little is known about cancer diagnosed during the medical evaluation of potential LTx candidates. What are the clinical, and …

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EXTERNAL VALIDATION OF THE CAPAD SCORE TO PREDICT THE OCCURRENCE OF PNEUMOTHORAX AFTER CT-GUIDED PERCUTANEOUS TRANSTHORACIC LUNG BIOPSY

Guillaume Eberst, Mohammad Waqaas, Alicia Guillien, Antoine Khalil et autres

Background: The most common complication preventing outpatient management after percutaneous CT-guided lung biopsy (PTLB) is the occurrence of pneumothorax requiring chest tube placement. We previously developed a pragmatic score to predict the risk of clinically relevant pneumothorax after PTLB (hereafter called the …

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Size-matching in lung transplantation by computed tomography for end-stage interstitial disease: a retrospective analysis

Mathieu Coblence, Harry Etienne, Arnaud Roussel, Quentin Pellenc et autres

Background: Size matching between donors and recipients is a major issue in lung transplantation (LTx), especially in patients with restrictive lung disease (RLD). This study aims to evaluate computed tomography (CT) as an additional method for defining the total lung capacity (TLC) …

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WHOLE-LUNG torsion following bilateral lung transplant, a rare complication: A case report

J. A. Stern, Antoine Khalil, Arnaud Roussel, Philippe Montravers

Whole lung torsion following bilateral lung transplant is a rare complication. This case report describes the diagnostic difficulties and consequences in a 59 year old patient. This study also includes a brief description of other cases in the literature.

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