The Amyotrophic Lateral Sclerosis M114T PFN1 Mutation Deregulates Alternative Autophagy Pathways and Mitochondrial Homeostasis
Elisa Teyssou, Laura Chartier, Delphine Roussel, Nirma D. Perera et autres
Mutations in profilin 1 (PFN1) have been identified in rare familial cases of Amyotrophic Lateral Sclerosis (ALS). PFN1 is involved in multiple pathways that could intervene in ALS pathology. However, the specific pathogenic role of PFN1 mutations in ALS is still not …
fr, au, gb (code pays fourni par la source)
21 citations
International Journal of Molecular Sciences