Magdalena Jaszek

Influence of Functional Additives with Potential Antimicrobial Properties on the Mechanical Performance and Accelerated Aging Resistance of (Meth)Acrylate-Based Composites

Karolina Kiełczewska-Klim, Andrzej Puszka, Magdalena Jaszek, Beata Podkościelna

The main aim of this study was to prepare and evaluate the physicochemical properties of new composite materials based on bisphenol A dimethacrylate modified with selected comonomers, namely 2-ethylhexyl acrylate (AEH), methyl methacrylate (MMA), 2-hydroxyethyl methacrylate (HEMA), and N-vinylpyrrolidone (NVP), and additives …

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Novel Antimicrobial Composites Modified with Nanosilver, CuSO4, Benzethonium Chloride, and ZnO

Karolina Kiełczewska-Klim, Beata Podkościelna, Katarzyna Szałapata, Monika Osińska‐Jaroszuk et autres

The antibiotic and drug resistance of various bacterial and fungal strains poses a significant challenge to medicine and industry. The subject of numerous studies is how to limit the spread of microorganisms and biofilm formation on various surfaces. This research focuses on …

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New Cross-Linked Polymeric Materials Modified with Antimicrobial Compounds in Relation to Their Biological Activities and Biodegradation by the Laccase-Producing Fungus Cerrena unicolor

Karolina Kiełczewska-Klim, Dawid Stefaniuk, Marcin Grąz, Rafał Typek et autres

This study characterizes novel cross-linked polymeric composites based on bisphenol A glycerolate dimethacrylate (BPA.DM) as the primary matrix, incorporating 1-vinyl-2-pyrrolidone (NVP) or 2-hydroxyethyl methacrylate (HEMA) as active diluents, and modified with antimicrobial agents: zinc oxide (ZnO), copper(II) sulfate (CuSO4), nanosilver (Ag), and …

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Zinc oxide-modified composites as a new antimicrobial coatings for application in biomedical industry – synthesis, thermal stability and antimicrobial properties

Karolina Młynarczyk, Beata Podkościelna, Monika Osińska-Jaroszuk, Katarzyna Szałapata et autres

Abstract In recent years, the incidence of hospital-acquired infections has been increasing, which may be caused by the emergence of antibiotic-resistant bacteria. A solution to this problem may be the synthesis of composites containing the addition of compounds with antimicrobial properties, which …

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Exploring the Anticancer Potential of Coriolus versicolor in Breast Cancer: A Review

Marta Ziaja‐Sołtys, Magdalena Jaszek

Breast cancer remains a leading cause of morbidity and mortality among women globally, with increasing incidence projected in the coming years. Despite advances in standard oncologic therapies, there is a growing interest in supportive interventions that enhance treatment efficacy and reduce adverse …

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Synteza i modyfikacja materiałów akrylowych stosowanych w protetyce stomatologicznej

Wojciech Pakaszewski, Bogdan Tarasiuk, Anna Szabelska, Karolina Młynarczyk et autres

Methyl methacrylate-based prosthetic materials are widely used in dentistry due totheir favorable aesthetics, ease of processing, and cost-effectiveness. However, their inherentbrittleness increases the risk of fractures during clinical use. In response to this limitation,current research efforts aim to improve not only the …

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Modulation of Abortiporus biennis Response to Oxidative Stress by Light as a New Eco-Friendly Approach with a Biotechnological Perspective

Anna Pawlik, Adrianna Rudawska, Anita Swatek, Grzegorz Janusz et autres

To comprehensively explore the impact of oxidative stress, induced by menadione and light at various wavelengths, on the metabolism and selected biochemical markers of the white rot fungus Abortiporus biennis, a phenotypic approach based on FF Panels and biochemical analysis was applied. …

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Is laccase from medicinal mushroom Cerrena unicolor cytotoxic to colon cancer cell line CT-26?

Daria Sondej, Dominika Pigoń-Zając, Magdalena Jaszek, Dawid Stefaniuk et autres

INTRODUCTION AND OBJECTIVE: Colorectal cancer takes an increasing toll every year. Despite the dynamic development of pharmacology, there is still no drug that would be strong enough to cause apoptosis of cancer cells, but at the same time would be free from …

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Mushrooms from genus Clitocybe and Tricholoma as potential new sources of CNS-active agents

Krzysztof Grzywnowicz, Zuzanna Bielak, Kevin Lewellyn, Jordan Zjawiony et autres

Novel CNS-stimulating activities were extracted from the fruit bodies of mushrooms from genus Clitocybe and Tricholoma. Fractions active against 5HT5A and 5HT2C receptors, and NET transporters were extracted with methanol, ethanol, cold water and hot water. Their 5HT receptors agonism and antagonism …

Novel Basidiomycetous Alcohol Oxidase from Cerrena unicolor—Characterisation, Kinetics, and Proteolytic Modifications

Sylwia Stefanek, Rafał Typek, Michał P. Dybowski, Dorota Wianowska et autres

Intracellular alcohol oxidase (AOX) was isolated from the basidiomycetous white rot fungus Cerrena unicolor FCL139. The enzyme was semi-purified (13-fold) using two-step chromatography with 30% activity recovery. The identity of the protein was confirmed by LC-MS/MS analysis, and its MW (72 kDa) …

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The anticancer activity of laccase from white rot fungus Cerrena unicolor on the example of its action on Caov-3 and NIH:OVCAR-3 ovarian cancer cells

Dominika Pigoń-Zając, Kamila Derlatka, Weronika Chuchmacz, Marika Kulczycka et autres

INTRODUCTION AND OBJECTIVE: According to epidemiological data, ovarian cancer is diagnosed in 240,000 women per year, which is why it is the seventh most common cancer among women worldwide. In addition, among gynaecological cancers it is characterized by the highest mortality. However, …

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Effectiveness of an ethanol extract of jet black ant nests for combatting nosemosis in apiary honey bees

Grzegorz Wagner, Magdalena Kunat-Budzyńska, Bernard Staniec, Anna Matuszewska et autres

Abstract An ethanol extract of Lasius fuliginosus ant nests was found to be highly effective against nosemosis in apiary honey bees. Two concentrations of the extract (300 mg and 1500 mg/100 ml sugar syrup) were tested on honey bees infected by nosemosis, …

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