Accès ouvert
2026
article
OpenAlex
Greta Rogani, Remco Erkens, Alejandra Bodelόn, Tim R. Mocking et autres
Objective Still disease (SD) is an autoinflammatory disorder characterized by remarkably high interleukin‐18 (IL‐18) levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated …
nl, it
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Freya M. C. H. Huijsmans, Tabea Thalheim, Alejandra Bodelόn, Greta Rogani et autres
Objective Still disease (SD) is an autoinflammatory syndrome characterized by innate immune dysregulation. Although complement can drive inflammation, its involvement in SD remains to be defined. Thus, we aimed to assess complement activation in SD. Methods Complement was assessed using transcriptomic, proteomic, …
nl, de, ca, ie
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Angela Markovska, Niels S. van Heusden, Dagmar Duijzer, Alejandra Bodelón et autres
Human CD4+ T cells utilize nutrients, including lipids, to support their activation and polarization. Considering the pivotal role of lipoproteins in lipid transport, we reasoned that lipoprotein uptake and processing could effect CD4+ T cell function. Here, we demonstrate that activation of …
nl, es
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Francesco Baldo, Remco Erkens, Mao Mizuta, Greta Rogani et autres
Objective: To assess current treatment in macrophage activation syndrome (MAS) worldwide and to highlight any areas of major heterogeneity of practice. Methods: A systematic literature search was performed in both EMBASE and PubMed databases. Paper screening was done by two independent teams …
it, nl, jp, de, hr
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Greta Rogani, Haeja Kessler, Bella Mehta, Elizabeth Baker et autres
Still's disease (SD) is now widely recognized as a single disease spectrum encompassing both childhood- and adult-onset forms. While most comparative studies so far have focused on clinical manifestations and treatment responses, aspects related to the pathophysiology of the disease including molecular …
nl, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Remco Erkens, Greta Rogani, Laura Huber, Anouk Verwoerd et autres
OBJECTIVE: To evaluate the applicability of the 2016 European Alliance of Associations for Rheumatology (EULAR)/American College of Rheumatology (ACR)/Paediatric Rheumatology International Trials Organisation (PRINTO) macrophage activation syndrome (MAS) classification criteria in patients with Still disease and systemic juvenile idiopathic arthritis (sJIA-SD) treated …
nl
(code pays fourni par la source)
Accès ouvert
2024
review
OpenAlex
Francesco Baldo, Remco Erkens, Mao Mizuta, Greta Rogani et autres
OBJECTIVE: To assess current treatment in macrophage activation syndrome (MAS) worldwide and to highlight any areas of major heterogeneity of practice. METHODS: A systematic literature search was performed in both EMBASE and PubMed databases. Paper screening was done by two independent teams …
it, nl, jp, de, hr, es, gb, in, us, il, se, tr, fr, ca, au
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Mattia Pozzato, Robertino Dilena, Greta Rogani, Gisella Beretta et autres
Behcet's disease (BD) is a rare vasculitis characterized by multisystemic inflammation. Central nervous system (CNS) involvement is rare and heterogeneous, particularly in the pediatric population. A diagnosis of neuro-Behcet could be highly challenging, especially if neurological manifestations precede other systemic features; however, …
it
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
A. Cappellari, Greta Rogani, Giovanni Filocamo, Antonella Petaccia
Objective: The purpose of this study was to investigate the effectiveness of corticosteroid therapy for children suffering from Sydenham chorea (SC). Methods: The design of the study was observational, retrospective and conducted at the single center of the Rheumatology Unit of Policlinic …
it
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Martina Rossano, Greta Rogani, Maria Maddalena D’Errico, Martina Cucchetti et autres
An association between infectious diseases and macrophage activation syndrome (MAS) has been reported, yet the exact role of infection in MAS development is still unclear. Here, a retrospective analysis of the clinical records of patients with rheumatic diseases complicated with MAS who …
it
(code pays fourni par la source)