Mary McMahon

NeuroDISK: An AI Approach to Automate Continuous Inquiry-Driven Discoveries in Neuroimaging Genetics

Daniel Garijo, Qifan Yang, Hernán Vargas, Shruti P. Gadewar et autres

Collaborative and multi-site neuroimaging studies have greatly accelerated the rate at which new and existing data can be aggregated to answer a neuroscientific question. New research initiatives are continuously collecting more data, allowing opportunities to refine previous published findings through continuous and …

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Career Development Practices: What Theories and Models Have to Offer

Nancy Arthur, Roberta Borgen, Mary McMahon

Career theory serves as a crucial foundation for practice, yet its relevance is sometimes questioned due to a perceived gap between theory and its practical application. We contend that the practical utility of theory should be a central criterion in evaluating contemporary …

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International data governance for neuroscience

Damian Eke, Amy Bernard, Jan G. Bjaalie, Ricardo Chavarriaga et autres

As neuroscience projects increase in scale and cross international borders, different ethical principles, national and international laws, regulations, and policies for data sharing must be considered. These concerns are part of what is collectively called data governance. Whereas neuroscience data transcend borders, …

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International Data Governance for Neuroscience

Damian Eke, Amy Bernard, Jan G. Bjaalie, Ricardo Chavarriaga et autres

As neuroscience projects increase in scale and cross international borders, different ethical principles, national and international laws, regulations, and policies for data sharing must be considered. These concerns are part of what is collectively called data governance. Whereas neuroscience data transcends borders, …

gb, us, no, ch, jp, au, ca (code pays fourni par la source)

Electronic health record and patterns of care for children with cerebral palsy

Brad G. Kurowski, Kelly Greve, Amy F. Bailes, Janet Zahner et autres

AIM: To characterize the patterns of care of children with cerebral palsy (CP) in a tertiary healthcare system. METHOD: Electronic health record data from 2009 to 2019 were extracted for children with CP. Machine learning hierarchical clustering was used to identify clusters …

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Structural Covariance Networks in Post-Traumatic Stress Disorder: A Multisite ENIGMA-PGC Study

Gopalkumar Rakesh, Mark W. Logue, Emily K. Clarke‐Rubright, Erin N. O’Leary et autres

Abstract Introduction Cortical thickness (CT) and surface area (SA) are established biomarkers of brain pathology in posttraumatic stress disorder (PTSD). Structural covariance networks (SCN) constructed from CT and SA may represent developmental associations, or unique interactions between brain regions, possibly influenced by …

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Altered fronto–limbic activity in children and adolescents with familial high risk for schizophrenia

Diana O. Perkins, Ayşenil Belger, Mary McMahon, Sarah J. Hart et autres

Early symptoms of schizophrenia tend to emerge during adolescence, which is a critical period for development of executive and emotional processing. While individuals with familial high risk (FHR) for schizophrenia may show cognitive and emotional changes, the neural mechanisms underlying the development …

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Mariko Weber, Joshua Bizzell, Hongbin Gu, Sarah J. Hart et autres

Adolescence is a critical developmental period where the early symptoms of schizophrenia frequently emerge. First-degree relatives of people with schizophrenia who are at familial high risk (FHR) may show similar cognitive and emotional changes. However, the neurological changes underlying the emergence of …

Mild Traumatic Brain Injury

Nicole Marcantuono, Mary McMahon

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Edith Hofer, Gennady V. Roshchupkin, Hieab H.H. Adams, Maria J. Knol et autres

Cortical thickness, surface area and volumes vary with age and cognitive function, and in neurological and psychiatric diseases. Here we report heritability, genetic correlations and genome-wide associations of these cortical measures across the whole cortex, and in 34 anatomically predefined regions. Our …

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Community‐Based Participatory Research: Engaging Youth to Provide Perspective on Risk and Protective Factors

Beth McMahon, Jennifer L. Rudella, Mary McMahon, Kara Wendling et autres

BACKGROUND: The Pennsylvania Youth Survey (PAYS) is administered biennially to adolescents; it covers knowledge, attitudes, and behaviors about risk and protective factors. PURPOSE: This study explored 8th, 10th, and 12th grade students' attitudes and beliefs about current trends regarding drugs, alcohol, and …

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The genetic architecture of the human cerebral cortex

Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro‐Conde et autres

INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities. Variations in human cortical surface area and thickness are associated with neurological, psychological, and behavioral traits and can be measured in vivo by magnetic resonance imaging (MRI). Studies in model organisms have identified …

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