Walter B. Cherny

Novel surgical approach for intraventricular cerliponase alfa enzyme replacement therapy via central venous access device (CVAD) port in neuronal ceroid lipofuscinosis type 2 (CLN2) disease

Scott Boop, Dominic Nistal, Adriel Barrios-Anderson, Walter B. Cherny et autres

INTRODUCTION: Neuronal ceroid lipofuscinosis type 2 (CLN2) is a genetic disease caused by deficiency of the enzyme tripeptidyl peptidase 1 (TPP1), resulting in seizures, vision/cognitive decline, and early death. Cerliponase alfa is an enzyme replacement therapy approved as treatment for CLN2 disease, …

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Cerliponase alfa for CLN2 disease, a promising therapy

Shawn C. Aylward, Jonathan Pindrik, Nicolas J. Abreu, Walter B. Cherny et autres

Introduction: Neuronal ceroid lipofuscinosis type 2 (CLN2) is a rare, lysosomal storage disease that causes progressive neurodegeneration in children. Cerliponase alfa enzyme replacement therapy is the first approved treatment for CLN2.Areas covered: This article reviews the clinical presentation of CLN2, significant preclinical …

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In vitro testing of current spread during ventricular catheter coagulation using diathermy

Frederick A. Boop, Azedine Medhkour, John Honeycutt, Charles A. James et autres

The authors report on the development of an anterior cerebral artery pseudoaneurysm that hemorrhaged after monopolar coagulation for a ventricular catheter lodged in the interhemispheric fissure. After observing this complication, the authors developed a simple bench test that can be performed by …

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Ruptured Intracranial Mycotic Aneurysm: An Unusual Infectious Complication following Craniofacial Surgery

Christopher M. Uchiyama, Douglas L. Brockmeyer, Walter B. Cherny, John J. L. Jacobs et autres

The case of a child with Apert syndrome is presented in which the development and rupture of an intracranial mycotic aneurysm occurred secondary to multiple infectious complications following craniofacial surgery. An endovascular procedure was utilized in an attempt to embolize the aneurysm …

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Book Review

Alan R. Cohen, Anthony Harris, Elad Levy, Emanuel Kanal et autres

The use of OctreoScan® in the preoperative diagnosis and postoperative follow up of meningiomas

Ali F. Krisht, Kevin Yoo, Walter B. Cherny, Ossama Al-Metty

Controlled lumbar drainage in pediatric head injury

Harold L. Rekate, Walter B. Cherny, Kim H. Manwaring, S. David Moss et autres

A retrospective study of external lumbar subarachnoid drainage in 16 pediatric patients with severe head injuries is presented. All patients had Glasgow Coma Scale scores of 8 or lower at 6 hours postinjury and were initially treated with ventriculostomy. Five patients required …

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Heterotopic pregnancy: Report of four cases

Steven J. Laband, Walter B. Cherny, Harris J. Finberg

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Thin-layer chromatography and false positive identification of phosphatidylglycerol in patients with preterm ruptured membranes

Charles M. Stedman, Scott A.G.M. Crawford, Walter B. Cherny

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Management of preterm premature rupture of membranes: Assessing amniotic fluid in the vagina for phosphatidylglycerol

Charles M. Stedman, Scott A.G.M. Crawford, Elise Staten, Walter B. Cherny

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Autonomic hyperreflexia in pregnancy and labor: A case report

Mahendra Nath, John M. Vivian, Walter B. Cherny

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Follow-up of patients with adenocarcinoma of the cervix and cervical stump

Charles H. Peete, F.Bayard Carter, Walter B. Cherny, Roy T. Parker

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