Elisabetta Tarentini

Metabolic Profile of Whole Unstimulated Saliva in Patients with Sjögren’s Syndrome

Giacomo Setti, Valeria Righi, Adele Mucci, Lucia Panari et autres

Primary Sjögren’s Syndrome (pSS) is a multi-system autoimmune disease that involves the exocrine glands. Lymphocytes infiltrate the gland tissue, leading to anatomical modification and hypofunction. Even if the prognosis of pSS is favorable, quality of life is typically reduced due to the …

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Current Knowledge in Skin Metabolomics: Updates from Literature Review

Alessia Paganelli, Valeria Righi, Elisabetta Tarentini, Cristina Magnoni

Metabolomic profiling is an emerging field consisting of the measurement of metabolites in a biological system. Since metabolites can vary in relation to different stimuli, specific metabolic patterns can be closely related to a pathological process. In the dermatological setting, skin metabolomics …

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Mesenchymal stromal cells promote the proliferation of basal stem cells and efficient epithelization in organotypic models of wound healing

Alessia Paganelli, Luisa Benassi, Elena Rossi, Elisabetta Tarentini et autres

Adipose derived mesenchymal stromal cells (ADSCs) represent a fascinating tool in the scenario of wound healing and regenerative medicine. Recent data already demonstrated that ADSCs could exert a stimulatory action on epithelial cells through secretion of soluble factors. The aim of the …

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Metabolomic Analysis of Actinic Keratosis and SCC Suggests a Grade-Independent Model of Squamous Cancerization

Valeria Righi, Camilla Reggiani, Elisabetta Tarentini, Adele Mucci et autres

Background-Actinic keratoses (AKs) are the most common sun-induced precancerous lesions that can progress to squamocellular carcinoma (SCC). Recently, the grade-independent association between AKs and SCC has been suggested; however, the molecular bases of this potential association have not been investigated. This study …

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335 Mesenchymal stem cells and acellular dermal matrices in wound healing: in vitro study of a combination treatment

Alessia Paganelli, Luisa Benassi, Elena Rossi, Elisabetta Tarentini et autres

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Use of confocal microscopy imaging for in vitro assessment of adipose‐derived mesenchymal stromal cells seeding on acellular dermal matrices: 3D reconstruction based on collagen autofluorescence

Alessia Paganelli, Elisabetta Tarentini, Luisa Benassi, Daniel Scelfo et autres

BACKGROUND: Both mesenchymal stromal cells (MSCs) and acellular dermal matrices (ADMs) represent fascinating therapeutic tools in the wound healing scenario. Strategies aimed at combining these two treatment modalities are currently under investigation. Moreover, scarcity of quantitative, nondestructive techniques for quality assessment of …

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Integrated metabolomic analysis and cytokine profiling define clusters of immuno-metabolic correlation in new-onset psoriasis

Elisabetta Tarentini, Giulia Odorici, Valeria Righi, Alessia Paganelli et autres

The association between the metabolic profile and inflammatory cytokines in psoriasis is poorly understood. We analyzed the metabolic and cytokine/chemokine profiles in serum and skin from patients with new-onset psoriasis and healthy subjects (n = 7/group) by HR-MAS NMR and Bio-Plex immunoassay. …

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Mesenchymal stem cells for the treatment of psoriasis: a comprehensive review

Alessia Paganelli, Elisabetta Tarentini, Luisa Benassi, Shaniko Kaleci et autres

Mesenchymal stem cells (MSCs) have recently been shown to have not only regenerative capabilities but also immunomodulating properties. For this reason, they are currently under investigation in clinical trials for the treatment of several autoimmune systemic disorders. Psoriasis is a systemic immune-mediated …

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Salivary 1H-NMR Metabolomics in Primary Sjögren Syndrome. Preliminary Results of a Pilot Case-Control Study

Giacomo Setti, Gilda Sandri, Elisabetta Tarentini, Lucia Panari et autres

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessExtended Abstract Salivary 1H-NMR Metabolomics in Primary Sjögren Syndrome. Preliminary Results of a Pilot Case-Control …

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Adipose-derived stem cells in wound healing: comparison with fibroblasts and keratinocytes interaction.

Luisa Benassi, Elisabetta Tarentini, Elena Rossi, Alessia Paganelli et autres

Adipose-derived stem cells (ADSCs) are a particular subset of mesenchymal stem cells present in the stromal-vascular fraction of the adipose tissue. These cells are considered very attractive for their relative abundance and accessibility in the human body. Keratinocytes and fibroblasts cells play …

648 Adipose-derived stem cells in wound healing: comparison with fibroblasts and keratinocytes interaction

Luisa Benassi, Elisabetta Tarentini, Elena Rossi, Alessia Paganelli et autres

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Field cancerization therapy with ingenol mebutate contributes to restoring skin-metabolism to normal-state in patients with actinic keratosis: a metabolomic analysis

Valeria Righi, Elisabetta Tarentini, Adele Mucci, Camilla Reggiani et autres

Actinic keratosis (AK) is a skin premalignant lesion, which progresses into squamous cell carcinoma (SCC) if left untreated. Ingenol mebutate gel is approved for local treatment of non-hyperkeratotic, non-hypertrophic AK; it also has the potential to act as a field cancerization therapy …

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