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Profil bibliographique

Walbert J. Bakker

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

29Publications signalées
1535Citations signalées
4Affiliations récentes

Les institutions déclarées

Les domaines associés

melanin and skin pigmentationCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCancer, Hypoxia, and MetabolismCutaneous Melanoma Detection and Management

Les publications récentes

Accès ouvert 2024 article OpenAlex

Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy

Marcella Willemsen, Jenny Bulgarelli, Sudhir Kumar Chauhan, Ragnhild Reehorst Lereim et autres

Background Tumor heterogeneity is a hurdle to effective therapy, as illustrated by the ‘mixed responses' frequently seen in immunotherapy-treated patients. Previously, AXL+ tumor cells were identified to be highly resistant to targeted therapy, whereas more differentiated MITF+ tumor cells do respond to …

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6 citations Immuno-Oncology Technology
Accès ouvert 2023 article OpenAlex

Immunity against Non-Melanoma Skin Cancer and the Effect of Immunosuppressive Medication on Non-Melanoma Skin Cancer Risk in Solid Organ Transplant Recipients

Walbert J. Bakker, Marcel W. Bekkenk, Rosalie M. Luiten

Non-melanoma skin cancers (NMSCs) occur frequently in the Caucasian population and are considered a burden for health care. Risk factors include ultraviolet (UV) radiation, ethnicity and immunosuppression. The incidence of NMSC is significantly higher in solid organ transplant recipients (SOTRs) than in …

nl (code pays fourni par la source)

14 citations Cells
Accès ouvert 2023 article OpenAlex

The Risk of Keratinocyte Cancer in Vitiligo and the Potential Mechanisms Involved

Alex Rooker, Wouter Ouwerkerk, Marcel W. Bekkenk, Rosalie M. Luiten et autres

Although light skin types are associated with increased skin cancer risk, a lower incidence of both melanoma and nonmelanoma skin cancer (NMSC) has been reported in patients with vitiligo. We performed a systematic review and meta-analysis on the NMSC risk in patients …

nl (code pays fourni par la source)

23 citations Journal of Investigative Dermatology
2022 article OpenAlex

Presence of Skin Tissue-Resident Memory T Cells in Human Nonmalignant and Premalignant Melanocytic Skin Lesions and in Melanoma.

Marcella Willemsen, Darryl Tio, Gabrielle Krebbers, Fazira R. Kasiem et autres

ABSTRACT: The infiltration of tissue-resident memory (TRM) cells in melanoma correlates with improved survival, suggesting an important role for TRM cells in immunity against melanoma. However, little is known about the presence of TRM cells in nonmalignant and premalignant melanocytic lesions. This …

nl (code pays fourni par la source)

6 citations PubMed
Accès ouvert 2022 article OpenAlex

Presence of Skin Tissue-Resident Memory T Cells in Human Nonmalignant and Premalignant Melanocytic Skin Lesions and in Melanoma

Marcella Willemsen, Darryl Tio, Gabrielle Krebbers, Fazira R. Kasiem et autres

Abstract: The infiltration of tissue-resident memory (TRM) cells in melanoma correlates with improved survival, suggesting an important role for TRM cells in immunity against melanoma. However, little is known about the presence of TRM cells in nonmalignant and premalignant melanocytic lesions. This …

nl (code pays fourni par la source)

8 citations American Journal of Dermatopathology

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