2026
article
OpenAlex
Thomas O. Vogler, Kiran U Dyamenahalli, Scott W. Mueller, Arek J. Wiktor et autres
Over the past five decades, advances in acute burn care have markedly improved early survival following severe thermal injury. However, long-term epidemiologic studies demonstrate that burn survivors remain at increased risk for metabolic disease, cardiovascular pathology, malignancy, cognitive impairment, and accelerated aging, …
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Accès ouvert
2026
preprint
OpenAlex
Casey L. Stewart, Michael M Morris, Alexandra E. Halevi, Amy M Moore et autres
Summary Peripheral nerve injury, whether caused by a cut, crush, or excessive stretch, can cause disordered regeneration and formation of a painful neuroma at the injury site. Regrowing axons may end in a swelling, hypersensitive nerve stump, producing pain along the affected …
us
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Accès ouvert
2026
conference-abstract
OpenAlex
Scott W. Mueller, Karrine D. Brade, Thomas Orion Vogler, Cameron Gibson et autres
Abstract Introduction Burn sepsis guidelines suggest a unit specific antibiogram for empiric antibiotic choices. Despite clinical observations regarding the ecology of burn infections, additional data are needed to justify unit specific antibiograms. Our objective was to create a burn (BICU) specific Gram-negative …
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Accès ouvert
2026
article
OpenAlex
Taryn Dee, Amber D Kohler, Cameron Gibson, Alexandra E. Halevi et autres
Abstract Patient Presentation (age range, injury details, relevant history) There were five patients who presented to our ABA certified burn center in 2024 who later developed signs and symptoms of folliculitis barbae (FB) or pseudofolliculitis barbae (PFB). All were male with an …
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Accès ouvert
2026
conference-abstract
OpenAlex
Justin Burleson, Scott W. Mueller, Arek J Wiktor, Fred Endorf et autres
Abstract Introduction A recent literature review revealed a lack of evidence regarding optimal timing for postoperative dressing removal following autograft surgery in burn patients. At our burn center, the decision for postoperative takedown (POTD) timing was left to individual provider preference—some preferring …
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Accès ouvert
2026
article
OpenAlex
Thomas Orion Vogler, Mara R Evans, Kevin M. Najarro, Rachel H. McMahan et autres
Abstract Introduction Growth differentiation factor 15 (GDF15) is a cytokine in the TGFβ superfamily whose expression is increased in response to cellular stress. In disease states such as cancer cachexia and cardiovascular disease, GDF15 acts both centrally and peripherally to mediate appetite, …
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Accès ouvert
2026
conference-abstract
OpenAlex
Sadie E. Larsen, Lacey Patton, Alexandra E. Halevi, Cameron Gibson et autres
Abstract Introduction Optimal nutrition is a critical component of burn care, essential for mitigating hypermetabolism, promoting wound healing, and improving outcomes. Total parenteral nutrition (TPN) is reserved for patients unable to meet their nutritional needs enterally, but its use has been associated …
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Accès ouvert
2026
conference-abstract
OpenAlex
Alexandra E. Halevi, Andrew J. Hoisington, Thomas Orion Vogler, Christopher E. Stamper et autres
Abstract Introduction Burn trauma induces a complex inflammatory response, including poorly-understood neuroinflammation. Our understanding of the effect of burn injury on neuroinflammation in patients is severely limited. The purpose of this study is to look at plasma markers of neuroinflammation in patients …
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Accès ouvert
2026
conference-abstract
OpenAlex
Arek J Wiktor, Scott W. Mueller, Blaire Balstad, Thomas Orion Vogler et autres
Abstract Introduction There is no consensus between use of fresh frozen plasma (FFP) and albumin (ALB) during acute burn resuscitation. The comparative impact on vascular endotheliopathy (ENDO) is also unknown. Our objective was to determine the efficacy and safety of FFP versus …
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2025
article
OpenAlex
Cameron Gibson, Scott W. Mueller, Emily Dorgan, Frederick W Endorf et autres
Enzymatic debridement with anacaulase-bcdb was approved by the US Food and Drug Administration in 2023. The purpose of this study is to compare outcomes from our first cohort of patients treated with this novel enzymatic agent. We compared patients treated with anacaulase-bcdb …
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Accès ouvert
2025
article
OpenAlex
Andrew J. Hoisington, Christopher E. Stamper, Molly J. Sullan, Lisa Anne Brenner et autres
BACKGROUND: Burn injury produces a complex biological response across multiple organs and biological systems. Nonetheless, current understanding regarding the neurologic response to burn injury is limited. Research suggests that disruption of the blood-brain barrier may play a role in central nervous system …
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2025
article
OpenAlex
Amber D Kohler, Scott W. Mueller, Naveen Kukreja, Thomas Orion Vogler et autres
Burn patients often require frequent moderate sedation for burn wound care procedures. The American Society of Anesthesiology recommends patients be made nil per os prior to moderate sedation. Here, we aimed to assess the risk of moderate sedation in burn patients with …
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