Radhia Bouzgarrou

Outcomes of Critically Ill Adult Patients With Acute Encephalitis

Romain Sonneville, Camille Couffignal, Bertrand Souweine, Suela Demiri et autres

Importance: Functional outcomes and long-term recovery after severe encephalitis are not well characterized. Objective: To determine the incidence of functional disability or death at 3 months and to describe recovery trajectories through 1 year after encephalitis. Design, Setting, and Participants: This prospective …

fr, ru (code pays fourni par la source)

Incidence of post-intensive care syndrome among patients admitted to post-ICU multidisciplinary consultations: the retrospective observational PICS-MIR study

Radhia Bouzgarrou, N. Farigon, Léo Morlat, Carole Philipponet et autres

To determine the prevalence of functional, respiratory and renal impairments and of post-intensive-care-syndrome (PICS) among patients who had attended a post-ICU multidisciplinary consultation (post-ICU-MC) around 3 months after ICU discharge, we performed a retrospective, monocentric observational study, at Clermont Ferrand University hospital, …

fr (code pays fourni par la source)

What is the functional impact of sarcopenia and myosteatosis three months after discharge to an intensive care population? A monocentric observational study

Margot Dressaire, Bertrand Souweine, Yves Boirie‌, Radhia Bouzgarrou et autres

Background & Aims Sarcopenia and myosteatosis are proving to be major factors to predict mortality in intensive care patients. Few studies are currently focusing on evaluating the functional impact after intensive care discharge and none has considered sarcopenia and myosteatosis as prognostic …

fr (code pays fourni par la source)

Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Critically Ill Patients: A Cluster Analysis According to Baseline Characteristics, Biological Features, and Chest CT Scan on Admission

Kévin Grapin, Romain De Bauchene, Benjamin Bonnet, Audrey Mirand et autres

BACKGROUND: Inconsistent results from COVID-19 studies raise the issue of patient heterogeneity. OBJECTIVE: The objective of this study was to identify homogeneous subgroups of patients (clusters) using baseline characteristics including inflammatory biomarkers and the extent of lung parenchymal lesions on CT, and …

fr (code pays fourni par la source)

Ultra-low tidal volume ventilation for COVID-19-related ARDS in France (VT4COVID): a multicentre, open-label, parallel-group, randomised trial

Jean‐Christophe Richard, Nicolas Terzi, Hodane Yonis, Fatima Chorfa et autres

fr (code pays fourni par la source)

Epidemiology and Outcome of Early-Onset Acute Kidney Injury and Recovery in Critically Ill COVID-19 Patients: A Retrospective Analysis

Alice Ruault, Carole Philipponnet, Vincent Sapin, Bertrand Evrard et autres

Background: The clinical significance of early-onset acute kidney injury (EO-AKI) and recovery in severe COVID-19 intensive care unit (ICU) patients is poorly documented. Objective: The aim of the study was to assess the epidemiology and outcome of EO-AKI and recovery in ICU …

fr (code pays fourni par la source)

Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial

Sylvie Chevret, Lila Bouadma, Claire Dupuis, Charles Burdet et autres

BACKGROUND: The respective benefits of high and low doses of dexamethasone (DXM) in patients with severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) and acute respiratory failure (ARF) are controversial, with two large triple-blind RCTs reaching very important difference in the effect-size. In …

fr (code pays fourni par la source)

Association of nitrogen balance trajectories with clinical outcomes in critically ill COVID-19 patients: A retrospective cohort study

Claire Dupuis, Alexandre Bret, Alexandra Janer, Olivia Guido et autres

fr (code pays fourni par la source)

High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure

Lila Bouadma, Armand Mekontso Dessap, Charles Burdet, Hamid Merdji et autres

Importance: The benefit of high-dose dexamethasone and oxygenation strategies vs standard of care for patients with severe acute hypoxemic respiratory failure (AHRF) caused by COVID-19 pneumonia is debated. Objectives: To assess the benefit of high-dose dexamethasone compared with standard of care dexamethasone, …

fr (code pays fourni par la source)

Remote ischemic conditioning in septic shock (RECO-Sepsis): study protocol for a randomized controlled trial

Martin Cour, Marielle Buisson, Kada Klouche, Radhia Bouzgarrou et autres

BACKGROUND: Septic shock is a major public health problem that is associated with up to 50% mortality. Unfavorable outcomes are mainly attributed to multiple organ failure (MOF) resulting from an uncontrolled inflammatory response and ischemia-reperfusion processes. REmote ischemic COnditioning (RECO) is a …

fr, us (code pays fourni par la source)