Noriyoshi Suya

名古屋大学タンデトロンAMS14Cシステムの現状と利用（2020）

Toshio Nakamura, Masayo Minami, Masako Yamane, Hirotaka Oda et autres

A Model 4130-AMS by High Voltage Engineering Europe B.V., dedicated to 14C measurements was delivered to Nagoya University in 1996/97. Acceptance tests of its performance were completed in 1999, and a routine operation started in mid-2000. The number of targets measured was …

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名古屋大学タンデトロンAMS14Cシステムの現状と利用（2019）

Toshio NAKAMURA, Masayo Minami, Hirotaka Oda, Akiko Ikeda et autres

A Model 4130-AMS by High Voltage Engineering Europe B.V., dedicated to 14C measurements was delivered to Nagoya University in 1996/97. Acceptance tests of its performance were completed in 1999, and a routine operation started in mid-2000. The number of targets measured was …

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量研放医研静電加速器施設（PASTA&SPICE）の現状2019

将一 及川, 酢屋 徳啓, 剛弘 石川, Hiroyuki Iso et autres

量子科学技術研究開発機構放射線医学総合研究所（量研放医研）の静電加速器施設（PASTA&SPICE）には、High Voltage Engineering Europe B. V. （HVEE）製のModel4117MC+タンデトロン加速器（最大ターミナル電圧1.7 MV）が設置されており、3 MeV程度の1H+を利用したマイクロPIXE分析やマイクロビーム細胞照射などの実験に広く利用されている 。 当施設のマイクロPIXE分析装置では、19F(p, p' γ)19F核反応により発生する110 keVの即発線をCdTe検出器（XR-100T-CdTe、Amptek製）を用いて検出する、フッ素のマイクロPIGE分析系を2016年度までに構築している。2017年度の本研究会では、19F(p, p' γ)19F核反応に共鳴幅の狭い複数の共鳴領域が存在する（例えば0.935 MeV、1.421MeV、1.940 MeV、2.322 MeV、2.563 MeV、2.783 MeV...etc）ことを活用して、当該マイクロPIGE分析系を用いた加速粒子のエネルギー絶対値測定について報告した。 前回の報告では、0.935 MeV、1.421MeV、1.940 MeV、2.322 MeV、2.563 MeV、2.783 MeVに相当する6つの共鳴ピークを観測していたが、2018年度に2.5 MeV～3.4 MeVの未計測であった範囲で共鳴領域探索を進め、新たに2.963 MeVに相当する共鳴ピークを観測することができた。観測された7つの共鳴ピーク対して、それぞれにガウス関数でフィッティングを行い、そのセントロイドから共鳴ピーク位置における1H+の加速エネルギー制御値を算出し、先行例データの共鳴エネルギー（絶対値）との比較を行った。その結果、加速エネルギー制御値が先行例データの絶対値に対して2 %程度大きく見積もられ、加速エネルギー（加速電圧）を過大に評価していることが判明した。 本稿では、量研放医研静電加速器施設（PASTA&SPICE）の2018年度利用状況及び最新のメンテナンス状況を紹介すると共に、加速粒子のエネルギー絶対値測定に関して現状で得られている結果を報告する。

Non-induction of radioadaptive response in zebrafish embryos by neutrons

P. Ng Candy Y., Kong Eva Y., Alisa Kobayashi, Noriyoshi Suya et autres

In vivo neutron-induced radioadaptive response (RAR) was studied using zebrafish (Danio rerio) embryos. The Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) facility at the National Institute of Radiological Sciences (NIRS), Japan, was employed to provide 2-MeV neutrons. Neutron doses of …

Non-induction of radioadaptive response in zebrafish embryos by neutrons

C. Y. P. Ng, Eva Yi Kong, Alisa Kobayashi, Noriyoshi Suya et autres

In vivo neutron-induced radioadaptive response (RAR) was studied using zebrafish (Danio rerio) embryos. The Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) facility at the National Institute of Radiological Sciences (NIRS), Japan, was employed to provide 2-MeV neutrons. Neutron doses of …

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Neutron induced bystander effect among zebrafish embryos

C. Y. P. Ng, Eva Yi Kong, Alisa Kobayashi, Noriyoshi Suya et autres

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Cellular localization of uranium in the proximal tubules and renal toxicity

Shino Homma‐Takeda, Kyoko Suzuki, Keisuke Kitahara, Benjamin J. Blyth et autres

The uses of uranium in the nuclear industry and military applications have led to growing public concern over its health effects. The kidney is known as the critical target for uranium toxicity. Uranium accumulates site-specifically into the S3 segments of the proximal …

Low-dose neutron dose response of zebrafish embryos obtained from the Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) facility

C. Y. P. Ng, Eva Yi Kong, Tomoya Konishi, Atsushi Kobayashi et autres

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Low-dose neutron dose response of zebrafish embryos obtained from the Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) facility

P. Ng C. Y., Kong Y, Teruaki Konishi, Alisa Kobayashi et autres

Cellular localization of uranium in the renal proximal tubules during acute renal uranium toxicity

Shino Homma‐Takeda, Keisuke Kitahara, Kyoko Suzuki, Benjamin J. Blyth et autres

Renal toxicity is a hallmark of uranium exposure, with uranium accumulating specifically in the S3 segment of the proximal tubules causing tubular damage. As the distribution, concentration and dynamics of accumulated uranium at the cellular level is not well understood, here, we …

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Micro-PIXE analysis system at NIRS-electrostatic accelerator facility for various applications

Masakazu Oikawa, Noriyoshi Suya, Teruaki Konishi, Takahiro Ishikawa et autres

A micro-PIXE analysis system based on the ion beam analysis system by Oxford Microbeams Ltd. has been developed at the NIRS-electrostatic accelerator facility. The introduction of the CdTe X-ray detector dramatically improved the detection efficiencies for heavy elements that are important in …

Research and development of focused proton microbeam irradiation system, SPICE for radio-biological studies.

Teruaki Konishi, Masakazu Oikawa, Noriyoshi Suya, Alisa Kobayashi et autres

There is continuing interest for the use of microbeam irradiation systems designed to deliver a defined number of charged particles on a single cell with a resolution of a few micrometers. Irradiation of an exact number of charged particles on a single …

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