Małgorzata Klimek

Atopic dermatitis and prematurity – a prospective study with analysis of the cytokine profile and thymus growth: a preliminary report

Aleksandra Kowalik, Kazimierz Węglarczyk, Małgorzata Klimek, Zofia Golińska et autres

Introduction: Preterm children suffer from atopic dermatitis (AD) less frequently than term children do. The reason for this phenomenon has not yet been identified. Hypotheses include changes in the T-helper 1 (Th1)/T-helper 2 (Th2) balance or altered development of the thymus. Aim: …

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Sequence variation analysis of the E1 and E2 genes of human papillomavirus type 16 in cervical lesions in women from the south of Poland

Katarzyna Sitarz, Jolanta Kopeć, Barbara Zawilińska, Małgorzata Klimek et autres

The E1 and E2 genes of the human papillomavirus encode the so-called early proteins, their sequences are conserved, and regulatory functions are associated with the viral oncoproteins. The purpose of this study is to determine the HPV16 E1 and E2 mutations appearing …

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Dual Switch in Lipid Metabolism in Cervical Epithelial Cells during Dysplasia Development Observed Using Raman Microscopy and Molecular Methods

Katarzyna Sitarz, Krzysztof Czamara, Joanna Białecka, Małgorzata Klimek et autres

Cellular lipid metabolism is significantly transformed during oncogenesis. To assess how dysplasia development influences lipid cellular metabolisms and what is the molecular background behind it, cervical epithelial cells of 63 patients assigned to seven groups (based on the cytological examination and HPVhr …

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Longitudinal assessment of cardiac function in extremely low-birth-weight children at 7 and 11 years of age: implications for adult medicine

Andrzej Grudzień, Mateusz Jagła, Małgorzata Klimek, Anna B. Knapp et autres

BACKGROUND: The long-term impact of extreme prematurity on cardiac structure and function has not been fully evaluated. AIMS: The aim of the study was to assess cardiac condition at 11 years of age in a local cohort of extremely low birth weight …

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Multimodal longitudinal respiratory function assessment in very low birth weight 7-year-old children

Wojciech Durlak, Małgorzata Klimek, Michał Wroński, Angelica Trybulska et autres

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Small for Gestational Age is an Independent Risk Factor for Neurodevelopmental Impairment

Joanna Hubert, Maja Gilarska, Małgorzata Klimek, Magdalena Nitecka et autres

Background: There is a deficit of publications regarding the impact of small for gestational age (SGA) on later neurodevelopment of premature infants and existing results are conflicting. Objectives: The aim of the present study was multifaceted neurodevelopmental assessment of children born prematurely, …

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Towards clean HSMG® graphene transfer

Dominika Kuten, Beata Nowacka, Marcin Pełka, Dominika Gnatek et autres

HPV Infection Significantly Accelerates Glycogen Metabolism in Cervical Cells with Large Nuclei: Raman Microscopic Study with Subcellular Resolution

Katarzyna Sitarz, Krzysztof Czamara, Joanna Białecka, Małgorzata Klimek et autres

Using Raman microscopy, we investigated epithelial cervical cells collected from 96 women with squamous cell carcinoma (SCC) or belonging to groups I, IIa, IIID-1 and IIID-2 according to Munich III classification (IIID-1 and IIID-2 corresponding to Bethesda LSIL and HSIL groups, respectively). …

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Somatic development and some indices of lipid metabolism in 11-year-old children born with extremely low birth weight (< 1000 g) (long-term cohort study).

Nina Mól, Magdalena Zasada, Małgorzata Klimek, Przemko Kwinta

AIM: To continue the prospective follow-up cohort study on the somatic development and lipid metabolic parameters of 11-year-old-children born with extremely low birth weight and to compare them with the results obtained in the study of 7-year-old children from the same group. …

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Usefulness of the most popular neurodevelopmental tests in preschool assessment of children born with very low birth weight

Maja Gilarska, Małgorzata Klimek, Magdalena Nitecka, Grażyna Dutkowska et autres

BACKGROUND: The aim of our study was multifaceted neurodevelopmental examination of children born prematurely with very low birth weight (VLBW) in order to evaluate the usefulness of popularly used tests. The second aim of the study was exploration of risk and protective …

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Comet assay is not useful to predict normal tissue response after radiochemotherapy in cervical and larynx cancer patients

Agnieszka Adamczyk, Beata Biesaga, Małgorzata Klimek, Anna Mucha-Małecka

Normal tissues reactions after radiotherapy vary considerably even between patients receiving the same treatment. The ability to predict the differences in radiosensitivity before radiotherapy would have important implication. Patients with squamous cell carcinoma of the: (i) cervix (38 patients) and (ii) larynx …

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Extremely Low Birth Weight Predisposes to Impaired Renal Health: A Pooled Analysis

Maja Gilarska, Anke Raaijmakers, Zhen‐Yu Zhang, Jan A. Staessen et autres

BACKGROUND: A number of studies examined the association between preterm delivery and kidney size and function later in life. However, the number of cases in published cohort studies is low. This study was aimed at performing a multicenter collaboration to pool data …

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