Richard M. Mangano

REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial

Maurizio Fava, Stephen M. Stahl, Luca Pani, Sara De Martin et autres

Objective: The purpose of this study was to examine the effects of REL-1017 (esmethadone), a novel N-methyl-d-aspartate receptor (NMDAR) channel blocker, in patients with major depressive disorder who failed to benefit from one to three standard antidepressant treatments in their current major …

us (code pays fourni par la source)

Mo2084 CB-5945 0.25 mg Twice Daily Is Associated With Significantly Increased Spontaneous Bowel Movement and Greater Proportion of Responders Compared With Placebo in Patients on Chronic Opioid Therapy for Noncancer Pain (45CL242; NCT01207427)

Neil Singla, Lee M. Techner, Kathie Gabriel, Richard M. Mangano

ADL5945, a potent orally bioavailable peripheral opioid receptor antagonist, improves bowel motility w/a low incidence/severity of GI AEs in a dose-dependent manner: results of 2 Ph 2 trials in opioid-induced constipation pts (45CL242 and 45CL243)

Lee M. Techner, Neil Singla, Katherin A. Gabriel, Richard M. Mangano

us (code pays fourni par la source)

A Double-Blind, Placebo-Controlled, Parallel-Group, Flexible-Dose Study of Venlafaxine Extended Release Capsules in Adult Outpatients With Panic Disorder

Michael R. Liebowitz, Gregory M. Asnis, Richard M. Mangano, Evan L. Tzanis

Article AbstractObjective: To evaluate the efficacy, safety, and tolerability of venlafaxine extended release (ER) in short-term treatment of panic disorder. Method: In this multicenter, double-blind study, conducted from April 2001 to December 2002, 343 adult outpatients who met criteria for panic disorder …

us (code pays fourni par la source)

A randomized controlled trial of venlafaxine ER and paroxetine in the treatment of outpatients with panic disorder

Mark H. Pollack, Richard M. Mangano, Richard Entsuah, Evan L. Tzanis et autres

us (code pays fourni par la source)

A randomized controlled trial of venlafaxine ER and paroxetine in the treatment of outpatients with panic disorder

Mark H. Pollack, Richard M. Mangano, Richard Entsuah, Evan L. Tzanis et autres

us, ca (code pays fourni par la source)

Predictors of clinical outcome in panic disorder: Analysis of venlafaxine XR short-term treatment studies

Mark H. Pollack, Dan J. Stein, Richard M. Mangano, Jeff J. Musgnung et autres

Cognitive behavioral therapy (CBT) is an effective treatment for many but not all patients with panic disorder. This raises the question of whether there are types of panic disorder for which CBT is effective, and other types for which it is ineffective. …

us, Afrique du Sud (code pays fourni par la source)

Relapse Prevention of Panic Disorder in Adult Outpatient Responders to Treatment With Venlafaxine Extended Release

James M. Ferguson, Arif Khan, Richard M. Mangano, Richard Entsuah et autres

OBJECTIVE: To compare the long-term efficacy of venlafaxine extended release (ER) with placebo in preventing panic disorder relapse in out-patient treatment responders. METHOD: Outpatients aged > or = 18 years who met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria …

us (code pays fourni par la source)

Sleep and Residual Sedation After Administration of Zaleplon, Zolpidem, and Placebo During Experimental Middle-of-the-Night Awakening

Gary K Zammit, Bruce C Corser, Karl Doghramji, June M. Fry et autres

us (code pays fourni par la source)

P.4.c.003 Predictors of clinical outcome in panic disorder: a pooled analysis of venlafaxine extended release short-term treatment studies

Mark H. Pollack, Dan J. Stein, Richard M. Mangano, Richard Entsuah et autres

A Randomized Controlled Trial of Venlafaxine Extended Release in Generalized Social Anxiety Disorder

Michael R. Liebowitz, Richard M. Mangano, Jacques Bradwejn, Gregory M. Asnis

BACKGROUND: Generalized social anxiety disorder is a debilitating psychiatric illness characterized by maladaptive thoughts about social situations. This double-blind study evaluated the anxiolytic efficacy, safety, and tolerability of venlafaxine extended release (ER) in adult out-patients with generalized social anxiety disorder. METHOD: Patients …

us (code pays fourni par la source)

Long-term use of sedative hypnotics in older patients with insomnia

Sonia Ancoli‐Israel, Gary S. Richardson, Richard M. Mangano, Lisa M. Miller Jenkins et autres

us (code pays fourni par la source)