Natalie Kostelecky

Epidemiology, ventilation, and outcomes of acute respiratory failure in immunocompromised patients from 103 intensive care units in 26 countries: a retrospective observational study

Elie Azoulay, Colleen McEvoy, Pedro Castro, Ali Ait Hssain et autres

Background Acute hypoxaemic respiratory failure (ARF) is the leading cause of intensive care unit (ICU) admission among immunocompromised patients. However, contemporary data regarding the epidemiology, management, and outcomes of ARF in this population remain scarce. We aimed to identify predictors of mortality …

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Six-Year Trends in ICU Admission, Management, and Outcomes of Chimeric Antigen Receptor T-Cell Patients in the ICU

Prabalini Rajendram, R. Scott Stephens, Anne Rain T. Brown, Heather P. May et autres

OBJECTIVES: To evaluate evolving management, ICU admission, and outcomes for critically ill chimeric antigen receptor (CAR) T-cell patients over a 6-year period. DESIGN: Multicenter retrospective cohort study from January 2018 to September 2023. SETTING: Eight U.S. centers. PATIENTS: Adult CAR T-cell patients …

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Assessment of Decision-Making Capacity in 97 Hospitalized Patients With Cancer: A Call for Standardization

Daniel C. McFarland, Yesne Alici, Natalie Kostelecky, Louis Voigt

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Impact of Delirium Onset and Duration on Mortality in Patients With Cancer Admitted to the ICU

Jing Tao, Kenneth Seier, Sanjay Chawla, Kay See Tan et autres

Background Little is known on the effects of delirium onset and duration on outcome in critically ill patients with cancer. Objectives To determine the impact of delirium onset and duration on intensive care unit (ICU) and hospital mortality and length of stay …

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Gender, Race, and Ethnicity in Critical Care Fellowship Programs in the United States From 2016 to 2021

Stephen M. Pastores, Natalie Kostelecky, Hao Zhang

IMPORTANCE: A diverse and inclusive critical care workforce is vital to the provision of culturally appropriate and effective care to critically ill patients of all backgrounds. OBJECTIVES: The purpose of this study is to determine the trends in gender, race, and ethnicity …

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Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors

Shawniqua Williams Roberson, Samuel Nwosu, Erin M. Collar, Amy L. Kiehl et autres

Importance: Sepsis is associated with long-term cognitive impairment and worse psychological and functional outcomes. Potential mechanisms include intracerebral oxidative stress and inflammation, yet little is known about the effects of early antioxidant and anti-inflammatory therapy on cognitive, psychological, and functional outcomes in …

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Delirium as a Risk Factor for Mortality in Critically Ill Patients With Cancer

Jing Tao, Kenneth Seier, Carina B. Marasigan-Stone, Justina-Sheila S. Simondac et autres

PURPOSE: Although delirium is known to negatively affect critically ill patients, little data exist on delirium in critically ill patients with cancer. METHODS: We analyzed 915 critically ill patients with cancer between January and December 2018. Delirium screening was performed using the …

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Indicators of Clinical Trajectory in Patients With Cancer Who Receive Cardiopulmonary Resuscitation

Sanjay Chawla, Cristina Gutiérrez, Prabalini Rajendram, Kenneth Seier et autres

BACKGROUND: Patients with cancer who require cardiopulmonary resuscitation (CPR) historically have had low survival to hospital discharge; however, overall CPR outcomes and cancer survival have improved. Identifying patients with cancer who are unlikely to survive CPR could guide and improve end-of-life discussions …

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1113: COVID REDUX: THE RISK TO CRITICALLY ILL CANCER PATIENTS REMAINS HIGH

Saad Ali, Nina Raoof, Saira Imran, Marina Kerpelev et autres

Introduction: Since the start of the COVID-19 pandemic there has been an evolution of variant strains that have spread throughout the world. As time has passed, clinicians have appreciated that these variants have different symptomology and clinical course. As our understanding of …

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Graduates of a Multidisciplinary Critical Care Training Program from 2000 to 2020: Looking at Their First Job

Stephen M. Pastores, Natalie Kostelecky, Neil A. Halpern

Abstract Background Little is known regarding the career paths of adult multidisciplinary critical care medicine (CCM) fellowship graduates. Objective The purpose of this study is to describe the demographic profiles and characteristics of the first jobs held by internal medicine–CCM fellowship graduates …

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Analysis of Intent and Reason for Oncologic Therapy Administration in Cancer Patients Admitted to the Intensive Care Unit

David Shaz, Stephen M. Pastores, Lokesh Dayal, Justin Berkowitz et autres

PURPOSE: To investigate the intent of, and reason for, administration of oncologic therapies in the intensive care unit (ICU). METHODS: Single center, retrospective, cohort study of patients with cancer who received oncologic therapies at a tertiary cancer center ICU between April 1, …

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Clinical Characteristics, Management, and Outcomes of Cancer Patients With Coronavirus Disease 2019 Admitted to the ICU

Michael K. M. Dang, Isha Bhatt, Alina Dulu, Hao Zhang et autres

Adult patients with cancer have a greater likelihood of developing severe illness and death from coronavirus disease 2019 compared with patients without cancer. We sought to characterize the clinical characteristics and outcomes of cancer patients who tested positive for severe acute respiratory …

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