Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion
Simon Keane, Ida Sjöberg, Lily Deland, Angelica Lindlöf et autres
0 citationsnpj Precision Oncology
Simon Keane
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22Publications signalées
104Citations signalées
2Affiliations récentes
Institutions déclarées
Domaines associés
Neuroblastoma Research and TreatmentsCancer, Hypoxia, and MetabolismGlioma Diagnosis and TreatmentIon channel regulation and functionCell death mechanisms and regulation
Publications récentes
Increased MLH1 , MGMT , and p16INK4a methylation levels in colon mucosa potentially useful as early risk marker of colon cancer
Yvonne Wettergren, P. Rolny, Helena Lindegren, Elisabeth Odin et autres
3 citationsMolecular & Cellular Oncology
P16.10.A UNRAVELING THE CLINICAL IMPLICATIONS OF TRIM24::NTRK2 FUSION GENE IN PEDIATRIC HIGH-GRADE GLIOMA: A CASE STUDY
Ida Karlsson, Simon Keane, Lily Deland, Angelica Lindlöf et autres
0 citationsNeuro-Oncology
A pilocytic astrocytoma with novel ATG16L1::NTRK2 fusion responsive to larotrectinib: a case report with genomic and functional analysis
Lily Deland, Simon Keane, Thomas Olsson Bontell, Tomas Sjöberg Bexelius et autres
4 citationsThe Oncologist
Bioinformatics analysis of miRNAs in the neuroblastoma 11q-deleted region reveals a role of miR-548l in both 11q-deleted and MYCN amplified tumour cells
Sanja Jurcevic, Simon Keane, Emmy Borgmästars, Zelmina Lubovac-Pilav et autres
0 citationsScientific Reports
Inflammation suppresses DLG2 expression decreasing inflammasome formation
Simon Keane, Matthew P. Herring, P. Rolny, Yvonne Wettergren et autres
20 citationsJournal of Cancer Research and Clinical Oncology
DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma
Simon Keane, Hendrik Weerd, Katarina Ejeskär
13 citationsDNA repair
Inflammation suppresses DLG2 expression, preventing inflammasome formation
Simon Keane, Matthew P. Herring, P. Rolny, Yvonne Wettergren et autres
0 citationsResearch Square
NovelTPR::ROS1Fusion Gene Activates MAPK, PI3K and JAK/STAT Signaling in an Infant-type Pediatric Glioma
Lily Deland, Simon Keane, Thomas Olsson Bontell, Henrik Fagman et autres
11 citationsCancer Genomics & Proteomics
DLG2 Impairs dsDNA Break Repair and Maintains Genome Integrity in Neuroblastoma
Simon Keane, Hendrik Weerd, Katarina Ejeskär
1 citationResearch Square
DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma
Simon Keane, Hendrik Weerd, Katarina Ejeskär
2 citationsResearch Square
The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma
Simon Keane, Tommy Martinsson, Per Kogner, Katarina Ejeskär
9 citationsCancer Cell International
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