Mansour Haeryfar

Investigating Homocitrulline-Specific T-Cell Responses in Rheumatoid Arthritis

Sofya Ulanova, G.C. Buckley, Mansour Haeryfar, Ewa Cairns et autres

Objectives Rheumatoid Arthritis (RA) is an incurable autoimmune disease affecting 1 in every 100 Canadians. Both B cells and T cells are involved in the pathogenesis of RA. These cells respond to peptides containing modified amino acids, including citrulline and homocitrulline. Although …

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Long Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis [Retraction] [Corrigendum]

Mengyan Zhang, Wei‐Guo Zhu, Mansour Haeryfar, Sumei Jiang et autres

[This corrects the article DOI: 10.2147/OTT.S474055.].

Long Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis [Retraction]

Mengyan Zhang, Wei‐Guo Zhu, Mansour Haeryfar, Sumei Jiang et autres

OncoTargets and Therapy is an international, peer-reviewed, open access journal focusing on the pathological basis of all cancers, potential targets for therapy and treatment protocols employed to improve the management of cancer patients. The journal also focuses on the impact of management …

Measles is highly contagious, but vaccine-preventable: A primer on recent outbreaks, transmission, symptoms and complications, including ‘immune amnesia’

Mansour Haeryfar

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614 Microbiome modification with fecal microbiota transplant from healthy donors before anti-PD1 therapy reduces primary resistance to immunotherapy in advanced and metastatic melanoma patients

Bertrand Routy, John Lenehan, Brendan A. Daisley, Meriem Messaoudene et autres

Background Microbiome-based interventions with fecal microbiota transplant (FMT) from treatment responders (R) have shown promising results in re-sensitizing anti-PD-1-refractory melanoma patients to anti-PD1 therapy. However, it is not currently known whether FMT can be used to prevent primary resistance. Here, we report …

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Preventing adverse events in patients with renal cell carcinoma treated with doublet immunotherapy using fecal microbiota transplantation (FMT): Initial results from perform a phase I study.

Ricardo Fernandes, Seema Nair Parvathy, D. Scott Ernst, Mansour Haeryfar et autres

4553 Background: The treatment landscape of metastatic renal cell carcinoma (mRCC) has evolved with the advent of either dual immune checkpoint inhibition (ICI) or in combination with Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor. Gut microbiota plays a central role in …

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Monovalent and Trivalent VSV-Based COVID-19 Vaccines Elicit Potent Neutralizing Antibodies and Immunodominant CD8 + T Cells Against Diverse SARS-CoV-2 Variants

Kate A. Parham, Gyoung Nyoun Kim, Nasrin Saeedian, Marina Ninkov et autres

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Long Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis

Mengyan Zhang, Wei‐Guo Zhu, Mansour Haeryfar, Sumei Jiang et autres

INTRODUCTION: The aim of this study was to investigate the role and mechanism of long non-coding RNA (lncRNA) TRG-AS1 in mediating the proliferation, invasion and migration of lung cancer cells as well lung tumor growth. METHODS: Firstly, the expression levels of TRG-AS1, …

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Chronic Stress Physically Spares But Functionally Impairs Innate-Like Invariant T Cells

Patrick T. Rudak, Joshua Choi, Katie M. Parkins, Kelly L. Summers et autres

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MAIT Cells Find Their Way Into Liver Metastases From Colorectal Cancer

Mansour Haeryfar

The liver is a popular destination for many spreading cancers, including colorectal carcinoma (CRC). This is not only owed to its anatomic location, but also likely due, at least partially, to its generally “tolerogenic” environment. Paradoxically, the liver is home to several …

Does accelerated liver hypertrophy caused by the ALPPS procedure lead to circulating tumour cell dissemination in patients with colorectal liver metastases?

Mauro Enrique Tun‐Abraham, Lori E. Lowes, Christopher R. Shaler, Kerollos Nashat Wanis et autres

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Canadian Surgery Forum1. (CJSEditors' Choice Award) Weight loss and obesity-related outcomes of gastric bypass, sleeve gastrectomy and gastric banding in patients enrolled in a population-based bariatric program: prospective cohort study2. Early outcomes of a small, rural bariatric surgery program3. Is early discharge of patients post-laparoscopic Roux-en-Y gastric bypass safe?4. Defining the learning curve: early experience of laparoscopic Roux-en-Y gastric bypass from a bariatric centre of excellence5. Bariatric surgery in patients with renal disease: Is it safe and is there an optimal approach?6. A comparison of weight loss and follow-up interventions required for sleeve gastrectomy and gastric bypass at a single centre: Is there an optimal procedure for Canada?7. Laparoscopic adjustable gastric band complication and revision rates in a publicly funded obesity program8. The Covidien TriStaple system versus the duet tissue buttress in laparoscopic sleeve gastrectomy: a comparative st

Richdeep S. Gill, Amy Bazzarelli, Andrew Smith, Anjana Munshi et autres

# 1. ( CJS Editors' Choice Award) Weight loss and obesity-related outcomes of gastric bypass, sleeve gastrectomy and gastric banding in patients enrolled in a population-based bariatric program: prospective cohort study {#article-title-2} Bariatric care is increasingly being delivered in Canada

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