Accès ouvert
2026
article
OpenAlex
Constanze A. Jakwerth, Sabina Illi, Helen Charles, Madlen Oelsner et autres
BACKGROUND: Preschool wheeze is heterogeneous and only a subset of children progresses to persistent asthma. We hypothesized that early-life wheeze reflects divergent airway epithelial maturation trajectories associated with distinct mucosal immune programs. METHODS: Nasal epithelial transcriptomes from 265 children and young adults …
de, us, ch
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Silvia Gschwendtner, Nicole Maison, Sabina Illi, Erika von Mutius et autres
Abstract Early-life wheezing in children has been associated with microbial alterations along the gut-airway axis, yet studies simultaneously investigating bacterial communities in both compartments remain scarce. The aim of this cross-sectional exploratory pilot study ( n = 25) was to characterize and …
de, ch
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Abstract Background The relevance of high-sensitivity C-reactive protein (hsCRP), a marker of low-grade systemic inflammation, remains unclear with regard to its association with severity and clinical outcomes in wheeze/asthma. We aimed to assess the role of hsCRP across different phenotypes and severity …
nl, de, ch, us, gr
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 1: Additional material including supplementary methods, legends of supplementary figures and supplementary tables.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 3: Supplementary Figure S2.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 2: Supplementary Figure S1.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Abstract Background The relevance of high-sensitivity C-reactive protein (hsCRP), a marker of low-grade systemic inflammation, remains unclear with regard to its association with severity and clinical outcomes in wheeze/asthma. We aimed to assess the role of hsCRP across different phenotypes and severity …
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 4: Supplementary Figure S3.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Abstract Background The relevance of high-sensitivity C-reactive protein (hsCRP), a marker of low-grade systemic inflammation, remains unclear with regard to its association with severity and clinical outcomes in wheeze/asthma. We aimed to assess the role of hsCRP across different phenotypes and severity …
de
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 1: Additional material including supplementary methods, legends of supplementary figures and supplementary tables.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 4: Supplementary Figure S3.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Lena Lagally, Lena Ullemeyer, Jimmy Omony, Kristina Laubhahn et autres
Supplementary Material 2: Supplementary Figure S1.
de
(code pays fourni par la source)