Benjamin Funke

No evidence to support the impact of migration background on treatment response rates and cancer survival: a retrospective matched-pair analysis in Germany

Roman Rüdiger, Franziska Geiser, Manuel Ritter, Peter Brossart et autres

BACKGROUND: Immigration has taken the central stage in world politics, especially in the developed countries like Germany, where the continuous flow of immigrants has been well documented since 1960s. Strikingly, emerging data suggest that migrant patients have a poorer response to the …

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High prevalence of comorbidities and use of concomitant medication in treated people living with HIV in Germany – results of the BESIDE study

Benjamin Funke, CD Spinner, Eva Wolf, Hans Heiken et autres

Due to demographic changes in people living with HIV (PLHIV), physicians are challenged with age-related comorbidities and their management. In the absence of comprehensive data collection, the burden of comorbidities and co-medication in addition to antiretroviral therapy (ART) remains unclear for the …

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High prevalence of recreational and illicit drug use in German people living with HIV with a potential for drug–drug interactions with antiretroviral therapy

Benjamin Funke, CD Spinner, H. J. Stellbrink, Albrecht D. Stoehr et autres

Recreational drug use is higher in people living with HIV (PLHIV) than in the general population in Europe. This use increases the risk for drug-drug interactions (DDIs) and adverse events. We assessed the prevalence and clinical consequences of substance abuse among PLHIV. …

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A Matched-pair Analysis on the Effect of Migration Background on Response Rates and Survival of Cancer Patients Treated at a Comprehensive Cancer Center in Germany

Roman Rüdiger, Franziska Geiser, Manuel Ritter, Peter Brossart et autres

Abstract Background: There are several studies that investigate health inequalities in Germany due to its being a destination for immigrants since the 1960s. In this study, we pay specific attention to differences in cancer survival between German patients with and without a …

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Higher number of multidisciplinary tumor board meetings per case leads to improved clinical outcome

Marius Freytag, Ulrich Herrlinger, Stefan Hauser, Franz Georg Bauernfeind et autres

BACKGROUND: This analysis aims at evaluating the impact of multidisciplinary tumor boards on clinical outcome of multiple tumor entities, the effect of the specific number of multidisciplinary tumor boards and potential differences between the tumor entities. METHODS: By a matched-pair analysis we …

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A matched-pair analysis on survival and response rates between German and non-German cancer patients treated at a Comprehensive Cancer Center

Marie K. Budde, Walther Christian Kuhn, Mignon-Denise Keyver-Paik, Friedrich Bootz et autres

BACKGROUND: Research shows disparities in cancer outcomes by ethnicity or socio-economic status. Therefore, it is the aim of our study to perform a matched-pair analysis which compares the outcome of German and non-German (in the following described as 'foreign') cancer patients being …

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Safety analysis of German real-life cohort WIP shows rates of neuropsychiatric events leading to discontinuation of raltegravir therapy below 2%

Uta Naumann, Arend Moll, D. Schleehauf, KT Lutz et autres

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Cross-sectional increase of adherence to multidisciplinary tumor board decisions

S. Hollunder, Ulrich Herrlinger, Matthias Zipfel, Jan Schmolders et autres

BACKGROUND: Cancer research has made great progress in the recent years. With the increasing number of options in diagnosis and therapy the implementation of tumorboards (TUBs) has become standard procedure in the treatment of cancer patients. Adherence tests on tumor board decisions …

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Similar efficacy and tolerability of raltegravir-based antiretroviral therapy in HIV-infected patients, irrespective of age group, burden of comorbidities and concomitant medication: Real-life analysis of the German ‘WIP’ cohort

Uta Naumann, Arend Moll, D. Schleehauf, Thomas A. Lutz et autres

Only limited efficacy and tolerability data on raltegravir (RAL) use are currently available. Study objectives were to describe the efficacy and tolerability profile of RAL-based antiretroviral therapy (ART) in routine clinical practice in Germany. The WIP study (WIP = "Wirksamkeit von Isentress …

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GLUTEN CONSUMPTION AT EARLY AGE IS DIFFERENT AMONG INFANTS FROM DIFFERENT EUROPEAN COUNTRIES. THE PREVENT-CD COHORTS

Pedro Augusto Crespo, José Ramón Calvo, Gemma Castillejo, Ednir Wanderley Martinez et autres

Maternal Decision Making Ability And Social Support : Associations With Infant Young Child Feeding And Nutrition In Rural Nicaragua

Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect

Annika Braun, Ulrike Schönfeld, Thilo Welsch, Martina Kadmon et autres

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Selective downregulation of retinoic acid-inducible gene I within the intestinal epithelial compartment in crohnʼs disease

Benjamin Funke, Felix Lasitschka, Wilfried Roth, Roland Penzel et autres

BACKGROUND: A defective innate immune response may contribute to the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC). Employing a global gene expression analysis, this study was aimed at identifying specifically regulated genes within the epithelial compartment in inflammatory bowel disease …

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